Zusammenfassung
□ Hintergrund
Wir berichten über eine typische Komplikation der arteriellen regionalen Chemotherapie der Leber (HAI) bei einem Patienten mit hepatisch metastasiertem Kolonkarzinom. Ein Jahr nach letzter HAI-Therapie zeigte der Patient Symptome einer akuten oberen gastrointestinalen Blutung. Endoskopisch war ein großes Ulcus duodeni mit Penetration in eine benachbarte Lebermetastase nachweisbar. Der Arteria-hepatica-katheter war im Bulbuslumen am Ulkusgrund sichtbar.
□ Schlußfolgerung
Patienten entwickeln in etwa 35% unter HAI-Therapie Ulcera ventriculi/duodeni. Der hier präsentierte Fall stellt in der Ausprägung allerdings eine seltene Komplikation dar.
Summary
□ Case Report
We report a typical complication of hepatic artery infusion therapy (HAI) in a patient with colon cancer metastatic to the liver. One year after the last HAI-therapy the patient presented with upper gastrointestinal bleeding. Endoscopy showed a large duodenic ulcer penetrating into an adjacent hepatic colon cancer metastasis. The hepatic artery catheter was visible at the ground of the duodenic ulcer.
□ Conclusion
Thirty-five percent of patients under HAI-therapy develop gastric/duodenic ulcers. The severity of the HAI complication presented here, however, is quite uncommon.
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Jäger, D., Warzelhan, J., Jäger, E. et al. Penetrierendes Ulcus duodeni als Komplikation eines Arteria-hepatica-Portkatheters bei hepatisch metastasiertem Sigmakarzinom. Med. Klin. 92, 680–682 (1997). https://doi.org/10.1007/BF03044825
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DOI: https://doi.org/10.1007/BF03044825