Abstract
The effect of three different anaesthetic techniques on the incidence and severity of postoperative emesis (nausea, retching and vomiting) was studied in 150 patients undergoing gynaecological laparoscopy. Patients were anaesthetized with isoflurane in nitrous oxide and oxygen (Group A), enflurane in nitrous oxide and oxygen (Group B) or with isoflurane in air and oxygen (Group C). Groups had been predetermined by date of birth. During the first 24 hours after the operation no difference was found at any time in the incidence or severity of emesis among the groups. The overall incidence of emesis during the first 24 hours postoperatively was 54, 48 and 52 per cent, in groups A, B and C, respectively. It is concluded that nitrous oxide does not increase the incidence of emesis after isoflurane anaesthesia and that isoflurane and enflurane anaesthesia are associated with similar incidences of nausea and vomiting after gynaecological laparoscopy.
Résumé
ľeffet de trois différentes techniques anesthésiques sur ľincidence et la sévérité du vomissement postopératoire (nausées, haut-le-cour et vomissements) a été étudié chez 150 patientes devant subir une laparoscopie pour opérations gynécologiques. Les patientes furent anesthésiées avec isoflurane, protoxyde ďazote et oxygène (Groupe A), enflurane, protoxyde ďazote et oxygène (Groupe B) ou avec isoflurane, air et oxygène (Groupe C). Les groupes ont été prédéterminés par la date de naissance. Durant les premières 24 heures postop aucune différence ne fut mentionnée en aucun temps sur ľincidence ou la sévérité des vomissements entre les groupes. ľincidence totale des vomissements durant les premières 24 heures postopératoires était de 54, 48 et 52 pour cent dans les groupes A, B et C respectivement. On conclut que le protoxyde ďazote n’augmente pas ľincidence des vomissements après ľanesthésie à V isoflurane et que ľanesthésie à ľisoflurane et ľnflurane est associée avec une incidence identique de nausées et vomissements après laparoscopie pour opération gynécologique.
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References
Korttila K, Kauste A, Auvinen J. Comparison on domperidone, droperidol, and metoclopramide in the prevention and treatment of nausea and vomiting after balanced general anaesthesia. Anest Analg 1979; 58: 396–400.
Korttila K, Kauste A, Tuominen M, Salo H. Droperidol prevents and treats nausea and vomiting after enflurane anaesthesia. Eur J Anaesth 1986; 2: 379–85.
Kauste A, Tuominen M, Heikkinen H, Gordin A, Korttila K. Droperidol, alitsapride and metoclopramide in the prevention and treatment of postoperative emetic sequelae. Eur J Anaesth 1986; 3: 1–9.
Alexander GD, Skupski JN, Brown EM. The role of nitrous oxide in postoperative nausea and vomiting. Anesth Analg 1984; 63: 175.
Korttila K, Hovorka J, Erkola O. Nitrous oxide does not increase the incidence of nausea and vomiting after isoflurane anesthesia. Anesth Analg 1987; 66: 761–5.
Lonie DS, Harper NJN. Nitrous oxide anaesthesia and vomiting. Anaesthesia 1986; 41: 703–7.
Melnik BM, Johnson LS. Effect of eliminating nitrous oxide in outpatient anesthesia. Anesthesiology 1987; 67: 982–4.
Bellville JW, Bross IDJ, Hawland WS. A method for the clinical evaluation of antiemetic agents. Anesthesiology 1959; 20: 753–60.
Muir JJ, Warner MA, Offort KP, Buck CV, Harper JV, Kunlcel SE. Role of nitrous oxide and other factors in postoperative nausea and vomiting: a randomized and blinded prospective study. Anesthesiology 1987; 66: 513–8.
Anderson R, Krogh K. Pain as a major cause of postoperative nausea. Can Anaesth Soc J 1976; 23: 366–9.
Fleiss JL. Statistical methods for rates and proportions. 2nd Edition New York. John Wiley and Sons. 1981, pp. 258–80.
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Hovorka, J., Korttila, K. & Erkola, O. Nitrous oxide does not increase nausea and vomiting following gynaecological laparoscopy. Can J Anaesth 36, 145–148 (1989). https://doi.org/10.1007/BF03011437
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DOI: https://doi.org/10.1007/BF03011437