Abstract
In a double blind study, seven volunteers were given lidocaine 0.75 per cent and bupivacaine 0.25 per cent in two trials to compare the agents for use in intravenous regional analgesia. There was no significant difference between the two agents in the duration of analgesia after removal of the tourniquet. Bupivacaine produced fewer side effects. It also consistently produced persistent analgesia on the posterolateral aspect of the forearm.
Résumé
Lors d’une étude à double insu, on a administré de la lidocaïne 0.75 pour cent et de la bupivacaéne 0.25 pour cent à sept volontaires en deux séances dans le but de comparer ces deux agents couramment utilisés pour l’anesthésie régionale intraveineuse. Une fois le garrot enlevé, on n’ a pas trouvé de différence significative entre les deux médicaments pour la durée de l’analgésie. La bupivacaïne a produit moins d’effets secondaires et a produit une analgésie persistante de la face postérolatérale de l’avant-bras.
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Enright, A.C., Smith, G.G. & Wyant, G.M. Comparison of bupivacaine and lidocaine for intravenous regional analgesia. Canad. Anaesth. Soc. J. 27, 553–555 (1980). https://doi.org/10.1007/BF03006884
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DOI: https://doi.org/10.1007/BF03006884