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Study of the oxidative metabolic function and chemotaxis of neutrophils from patients with cancer influenced by Selenium Yeast

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Abstract

The effects of Selenium Yeast (SY) given orally to patients with cancer on the oxidative metabolic function and chemotaxis of neutrophils were studied by Lumino-dependent Chemiluminescence (CL) assay and agarose plates assay, respectively. The results showed that the background CL and the peak value CL of neutrophils from patients with cancer 14 d after taking SY were, on the average, 4 and 1.2 times higher than those before taking SY. The chemotactic index (CI) and chemotactic differential (CD) increased in response to SY supplementation; the differences are statistically significant (p<0.01), and no corresponding differences could be seen in the control group (taking yeast).

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Authors and Affiliations

  1. Huazhong University of Science and Technology, Wuhan, People's Republic of China

    Huibi Xu

  2. Anhui Medical University, Hefei, People's Republic of China

    Weide Mei, Zhaoming Dong & Baoliang Liao

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  1. Huibi Xu
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  2. Weide Mei
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  3. Zhaoming Dong
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  4. Baoliang Liao
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Xu, H., Mei, W., Dong, Z. et al. Study of the oxidative metabolic function and chemotaxis of neutrophils from patients with cancer influenced by Selenium Yeast. Biol Trace Elem Res 25, 201–209 (1990). https://doi.org/10.1007/BF02990415

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  • DOI: https://doi.org/10.1007/BF02990415

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