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Tc-99m MDP bone scintigraphy of myositis as a manifestation of chronic graft-versus-host disease after non-myeloablative peripheral stem cell transplantation

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Abstract

A 27-year-old man developed polymyositis as a manifestation of chronic graft-versus-host disease (GVHD) after non-myeloablative peripheral blood stem cell transplantation (PBSCT). Bone scintigraphy showed intense, striped, and heterogeneous accumulation of Tc-99m methylene diphosphonate (MDP) in the soft-tissue of his lower limbs, while faint activities were seen in the right upper limb. Tc-99m MDP scintigraphy was very useful for accurate and objective evaluation of the severity of the muscle injury and the extent of polymyositis caused by chronic GVHD.

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Authors and Affiliations

  1. Department of Medical Imaging, Sapporo City General Hospital, N-11, W-13, 060-8604, Sapporo, Japan

    Maki Mitomo, Chihoko Miyazaki, Yohko Usami, Shunsuke Nagano, Noriko Nakamura & Kohzoh Kubo

  2. Department of Clinical Immunology and Hematology, Sapporo City General Hospital, Japan

    Masaya Mukai

Authors
  1. Maki Mitomo
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  2. Chihoko Miyazaki
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  3. Masaya Mukai
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  4. Yohko Usami
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  5. Shunsuke Nagano
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  6. Noriko Nakamura
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  7. Kohzoh Kubo
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Correspondence to Chihoko Miyazaki.

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Mitomo, M., Miyazaki, C., Mukai, M. et al. Tc-99m MDP bone scintigraphy of myositis as a manifestation of chronic graft-versus-host disease after non-myeloablative peripheral stem cell transplantation. Ann Nucl Med 19, 41–45 (2005). https://doi.org/10.1007/BF02986334

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  • DOI: https://doi.org/10.1007/BF02986334

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