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Accuracy of mutation rates

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Summary

The use of the standard error of estimates of mutation rates, and other small proportions, is shown to be highly erroneous. A table is provided for rapidly making the exact tests of significance.

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References

  • Fisher, R. A. &Yates, F. (1941).Statistical Tables for Biological, Agricultural and Medical Research, 2nd ed. (in the Press). Edinburgh: Oliver and Boyd.

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  • Muller, H. J. (1940). An analysis of the process of structural change in chromosomes inDrosophila.J. Genet. 40, 1–66.

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  • Timoféeff-Ressovsky, N. W.,Zimmer, K. G. &Delbruck, M. (1935). Über die Natur der Genmutation und der Genstruktur.Nach. Ges. Wiss. Göttingen F.G.6.

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Authors and Affiliations

  1. Statistical Department, Rothamsted Experimental Station, Harpenden, Herts

    W. L. Stevens

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  1. W. L. Stevens
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Stevens, W.L. Accuracy of mutation rates. Journ. of Genetics 43, 301–307 (1942). https://doi.org/10.1007/BF02982905

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  • DOI: https://doi.org/10.1007/BF02982905

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