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Inherited macrocytic anaemias in the house mouse

II. Dominance relationships

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Summary

The geneW in the mouse has no measurable effect on the blood in heterozygotes, regardless of the amount of variegation present. Mice heterozygous forW V have macrocytic red blood corpuscles without being appreciably anaemic. It is suggested that this effect may somehow be causally connected with the general dilution of fur colour found in these heterozygotes, though the nature of this relation remains obscure. There is no evidence that the variegation ofW/+ orW V/+ is caused by an anaemia.

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Authors and Affiliations

  1. Department of Biometry, University College, London

    Hans Grüneberg

  2. Pathology Laboratory, Mount Vernon Hospital, Northwood, Middlesex

    Hans Grüneberg

Authors
  1. Hans Grüneberg
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Grüneberg, H. Inherited macrocytic anaemias in the house mouse. Journ. of Genetics 43, 285–293 (1942). https://doi.org/10.1007/BF02982903

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  • DOI: https://doi.org/10.1007/BF02982903

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