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Diffuse Large B-Cell Lymphoma: Insights Gained from Gene Expression Profiling

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Abstract

Analysis of global gene expression with DNA microarrays has great potential to improve the understanding of tumorigenesis, advance tumor diagnosis and classification, and affect cancer treatment. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin’s lymphoma. However, we now realize that the disease is extremely heterogeneous. This review summarizes the progress in understanding DLBCL that has been made as a result of the application of gene expression profiling.

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Authors and Affiliations

  1. Department of Hematology and Oncology, University of Miami, Sylvester Comprehensive Cancer Center, 1475 NW 12th Ave (D8-4), 33136, Miami, FL, USA

    Izidore S Lossos

  2. Division of Oncology, Department of Medicine, Stanford University Medical Center, Stanford, California, USA

    Ronald Levyb

Authors
  1. Izidore S Lossos
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  2. Ronald Levyb
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Lossos, I.S., Levyb, R. Diffuse Large B-Cell Lymphoma: Insights Gained from Gene Expression Profiling. Int J Hematol 77, 321–329 (2003). https://doi.org/10.1007/BF02982638

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  • DOI: https://doi.org/10.1007/BF02982638

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