Skip to main content
Log in

Neem and other Botanical insecticides: Barriers to commercialization

  • Minireview
  • Published:
Phytoparasitica Aims and scope Submit manuscript

Abstract

In spite of the wide recognition that many plants possess insecticidal properties, only a handful of pest control products directly obtained from plants,i. e., botanical insecticides, are in use in developed countries. The demonstrated efficacy of the botanical neem (based on seed kernel extracts ofAzadirachta indica), and its recent approval for use in the United States, has stimulated research and development of other botanical insecticides. However, the commercialization of new botanical insecticides can be hindered by a number of issues. The principal barriers to commercialization of new botanicals are (i) scarcity of the natural resource; (ii) standardization and quality control; and (iii) registration. These issues are no problem (i) or considerably less of a problem (ii, iii) with conventional insecticides. In this review I discuss these issues and suggest how the problems may be overcome in the future.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Alford, A. R., Cullen, J. A., Storch, R. H. and Bentley, M. D. (1987) Antifeedant activity of limonin against the Colorado potato beetle (Coleoptera: Chrysomelidae).J. Earn. Entomol. 80:575–578.

    CAS  Google Scholar 

  2. Arnason, J. T., Philogene, B. J. R. and Morand, P. [Eds.] (1989) Insecticides of Plant Origin. ACS Symp. Ser. 387.

  3. Assabgui, R., Lorenzetti, R., Terradot, L., Regnault-Roger, C, Malo, N., Wiriyachitra, P., Sanchez-Vindas, P. E., San Roman, L., Isman, M. B., Durst, T. and Arnason, J. T. (1997) Efficacy of botanicals from the Meliaceae and Piperaceae.in:Hedin, P. A., Hollingworth, R. M., Masler, E. P., Miyamoto, J. and Thompson, D. G. [Eds.]Phytochemicals for Pest Control.ACS Symp. Ser. 658:38–48.

    Google Scholar 

  4. Berenbaum, M. (1985) Brementown revisited: interactions among allelochemicals in plants.Recent Adv. Phytochem. 19:139–169.

    CAS  Google Scholar 

  5. Chen, W., Isman, M. B. and Chili, S. -F. (1995) Antifeedant and growth inhibitory effects of the limonoid toosendanin andMelia toosendan extracts on the variegated cutworm,Peridmma saucia (Lepidoptera: Noctuidae).J. Appl. Entomol. 119:367–370.

    Article  Google Scholar 

  6. Feng, R. and Isman, M. B. (1995) Selection for resistance to azadirachtin in the green peach aphidMyzus persicae.Experientia 51:831–833.

    Article  CAS  Google Scholar 

  7. Gentry, A. H. (1993) Tropicalforest diversity and the potential for new medicinal plants.in: Kinghorn, A. D. and Balandrin, M. F. [Eds.] Human Medicinal Agents from Plants.ACS Symp. Ser. 543:13–24.

  8. Hull, C. J. Jr., Dutton, W. R. and Switzer, B. S. (1993) Quantification of azadirachtins in insecticidal formulations by high-performance liquid chromatography.J. Chromatogr. 633:300–304.

    Article  CAS  Google Scholar 

  9. Isman, M. B. (1995) Leads and prospects for the development of new botanical insecticides.Rev. Pestic. Toxicol. 3:1–20.

    CAS  Google Scholar 

  10. Isman, M. B., Arnason, J. T. and Towers, G. H. N. (1995) Chemistry and biological activity of ingredients of other species of Meliaceae.in: Schmutterer, H. [ED.] The Neem TreeAzadirachta indica A. Juss. and Other Meliaceous Plants. Sources of Unique Natural Products for Integrated Pest Management, Medicine, Industry and Other Purposes. VCH, Weinheim, Germany. pp. 652–666.

    Google Scholar 

  11. Isman, M. B., Gunning, P. J. and Spollen, K. M. (1997) Tropical timber species as sources of botanical insecticides. in: Hedin, P. A., Hollingworth, R. M., Masler, E. P., Miyamoto, J. and Thompson, D. G. [Eds.] Phytochemicals for Pest Control.ACS Symp. Ser. 658:27–37.

  12. Klocke, J. A. and Kubo, I. (1982) Citrus limonoid by-products as insect control agents.Entomol. Exp. Appl. 32:299–301.

    CAS  Google Scholar 

  13. McLaughlin, J. L., Zeng, L., Oberlies, N. H., Alfonso, D., Johnson, H. A. and Cummings, B. A. (1997) Annonaceous acetogenins as new pesticides: recent progress.in: Hedin, P. A., Hollingworth, R. M., Masler, E. P., Miyamoto, J. and Thompson, D. G. [Eds.] Phytochemicals for Pest Control.ACS Symp. Ser. 658:117–133.

  14. Morgan, E. D., van der Esch, S. A., Jarvis, A. P., Maccioni, O., Giagnacovo, G. and Vitale, F. (1996) Production of natural insecticides fromAzadirachta species by tissue culture.Abstr. Int. Neem Conf. (Gatton, Qld., Australia), p. 29.

    Google Scholar 

  15. Van Beek, T. A. and Breteler, H. [Eds.] (1993) Phytochemistry and Agriculture. Clarendon Press, Oxford, UK.

    Google Scholar 

  16. Wink, M. (1993) Production and application of phytochemicals from an agricultural perspective.in: van Beek, T. A. and Breteler, H. [Eds.] Phytochemistry and Agriculture. Clarendon Press, Oxford, UK. pp. 171- 213.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Murray B. Isman.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Isman, M.B. Neem and other Botanical insecticides: Barriers to commercialization. Phytoparasitica 25, 339–344 (1997). https://doi.org/10.1007/BF02981099

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02981099

Key words

Navigation