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Synthesis of new salicylamide derivatives with evaluation of their antiinflammatory, analgesic and antipyretic activities

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  • Medicinal Chemistry & Natural Products
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Abstract

A new series of pyridazine, pyrazoles, pyrazolidine-3,5-dione, Semicarbazide, thiosemicarbazides, hydantoin, thiohydantoins, 1,2,4-triazoles, S-triazolo[3,4-b]-1,3,4-thiadiazoles incorporated indirectly into salicylamide moiety at position 2 were synthesized. Also the synthesis of novel series of 3-salicylamido-2-hydroxypropyl-amine derivatives were prepared. Several of these compounds were screened for antiinflammatory, analgesic, antipyretic and ulcerogenic activities.

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Correspondence to H. H. Fahmy.

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Fahmy, H.H., Soliman, G.A. Synthesis of new salicylamide derivatives with evaluation of their antiinflammatory, analgesic and antipyretic activities. Arch Pharm Res 24, 180–189 (2001). https://doi.org/10.1007/BF02978253

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  • DOI: https://doi.org/10.1007/BF02978253

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