Abstract
The chromatographic separation of the MeOH extract from the aerial parts ofSyneilesis palmata led to the isolation of a new sesquiterpene glycoside4, together with four known compounds. Their structures were characterized to be 4β,5β-epoxy-caryophill-8,(15)-ene (1), 3β-hydroxy-gultin-5-ene (2), 4α,5β-dihydroxy-caryophill-8,(15)-ene (3), (-)-oplopan-4-one-10-α-O-β-D-glucose (4) and 3-hexenyl-1-O-β-D-glucopyranose (5), based on spectroscopic and chemical methods. Compound2 showed moderate cytotoxicity against five human tumor cell linesin vitro with its ED50 values ranging from 5.90∼10.83 μg/mL.
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Lee, K.H., Choi, S.U. & Lee, K.R. Sesquiterpenes fromSyneilesis palmata and their cytotoxicity against human cancer cell linesin vitro . Arch Pharm Res 28, 280–284 (2005). https://doi.org/10.1007/BF02977792
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DOI: https://doi.org/10.1007/BF02977792