Abstract
Systematic fractionation ofAngelica gigas roots led to the isolation of linear furano(pyrano)coumarins such as bergapten (1), decursinol angelate (2), decursin (3), nodakenetin (4) and nodakenin (5). The antibacterial activities of those compounds against pathogenic bacteria were investigated. Among the compounds tested, decursinol angelate (2) and decursin (3) exhibited significant antibacterial activity againstBacillus subtilis with the minimum inhibitory concentrations (MICs) of 50 and 12.5 μg/mL, respectively.
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Lee, S., Shin, D.S., Kim, J.S. et al. Antibacterial coumarins fromAngelica gigas roots. Arch Pharm Res 26, 449–452 (2003). https://doi.org/10.1007/BF02976860
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DOI: https://doi.org/10.1007/BF02976860