Abstract
The anti-oxidant activities of fucosterol isolated from the marine algaePelvetia siliquosa were investigated. Fucosterol exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by CCI4-intoxication in rats. Fucosterol inhibited the sGOT and sGPT activities by 25.57 and 63.16%, respectively. Fucosterol showed the increase in the anti-oxidant enzymes such as hepatic cytosolic superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-px) activities by 33.89, 21.56 and 39.24%, respectively, in CCI4-intoxicated rats. These results suggest that fucosterol possess not only the anti-oxidant, but also the hepatoprotective activities in rats.
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Lee, S., Lee, Y.S., Jung, S.H. et al. Anti-oxidant activities of fucosterol from the marine algaePelvetia siliquosa . Arch Pharm Res 26, 719–722 (2003). https://doi.org/10.1007/BF02976680
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DOI: https://doi.org/10.1007/BF02976680