Abstract
In a bioassay-guided search for anti-allergic compounds from higher plants of Korea, polymethoxyflavones, 3′,4′,5,6,7,8-hexamethoxyflavone (I), 5-hydroxy-3′,4′,6,7,8-pentamethoxyflavone (II) and 3′,4′,5,7,8,-pentamethoxyflavone (III) have been isolated from the immature peels ofCitrus unshiu. Structures of these compounds were elucidated on the basis of spectroscopic techniques. CompoundsI andII inhibited dose-dependently histamine release from the rat peritoneal mast cells activated by compound 48/80 or anti-DNP IgE.
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Kim, D.K., Lee, K.T., Eun, J.S. et al. Anti-allergic components from the peels ofCitrus unshiu . Arch Pharm Res 22, 642–645 (1999). https://doi.org/10.1007/BF02975340
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DOI: https://doi.org/10.1007/BF02975340