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Outcome of pregnancy following renal transplantation

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Summary

Successful renal transplantation improves fertility with 1 in 50 women of childbearing age becoming pregnant. Pregnancy following renal transplantation is associated with increased maternal and fetal complications. In Belfast 118 women of childbearing age (15–45 yrs) have received a renal allograft and of these 14 (12%) have become pregnant. Twenty-seven pregnancies have resulted in 23 live births (including one set of identical twins), 1 still birth and 4 first trimester abortions. The most frequent complications were hypertension and prematurity. In this group of patients, whose sole immunosuppressive therapy was azathioprine and prednisolone, pregnancy post transplantation was associated with frequent successful outcome and a low incidence of maternal and fetal complications.

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Authors and Affiliations

  1. Regional Nephrology Unit. Level 11, Tower Block, Belfast City Hospital, Ireland

    J. H. Brown & A. P. Maxwell

  2. Departmant of Medicine, The Queen’s University of Belfast, Ireland

    M. G. McGeown

Authors
  1. J. H. Brown
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  2. A. P. Maxwell
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  3. M. G. McGeown
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Brown, J.H., Maxwell, A.P. & McGeown, M.G. Outcome of pregnancy following renal transplantation. I.J.M.S. 160, 255–256 (1991). https://doi.org/10.1007/BF02973400

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  • DOI: https://doi.org/10.1007/BF02973400

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