Skip to main content
Log in

Mycobacterium paratuberculosis isole chez des patients atteints de maladie de Crohn Résultats préliminaires

Mycobacterium paratuberculosis isolated from patients with Crohn ’s disease

Mycobacterium paratuberculosis aislado en pacientes con Enfermedad de Crohn. Resultados preliminares

  • Published:
Acta Endoscopica

Résumé

En 1913, Dalziél a décrit des observations compatibles avec une maladie de Crohn vraisemblablement en rapport avec une paratuberculose.

En 1984, Chiodini a isolé un Mycobacterium paratuberculosis chez des patients atteints de maladie de Crohn. Entre 1985 et 1990, nous avons isolé ’ trois souches de Mycobacterium paratuberculosis.

Depuis 1986, 4 autres groupes ont confirmé les résultats initiaux de Chiodini. Une étiologie microbienne de la maladie de Crohn, spécialement en rapport avec une mycobacterie type M. paratuberculosis, semble fondée sur des arguments de plus en plus prometteurs.

Summary

En 1913, Dalziel described cases of probably Crohn ’ s disease, which could be related to paratuberculosis. In 1984 Chiodini isolated Mptbc from Crohn ’ a patients. We isolated between 1985-1990 3 strains of Mptbc. Since 1986 4 other groups confirmed the original results of Chiodini. Considering all possibilities a microbial aetiology, especially a mycobacterial one connected with Mptbc, seems more and more promising.

Resumen

En 1913, Dalziel describió observaciones compatibles con una probable Enfermedad de Crohn relacionada con una paratuberculosis. En 1984, Chiodini aisló un Mycobacterium paratuberculosis en pacientes con Enfermedad de Crohn. Entre 1985 y 1990 hemos aislado trescepas de Mycobacterium tuberculosis.

Después de 1986, otros 4 grupos han confirmado los resultados iniciales de Chiodini. Una etiología microbiana de la Enfermedad de Crohn, especialmente relacionada con una micobacteria tipo M. paratuberculosis parece sostenida sobre bases más y más promisorias.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Références

  1. DALZIEL T.K. — Chronic interstitial enteritis.BMJ, 1913, 2, 1068–1070.

    Google Scholar 

  2. VAN PATTER W. . — Pathology and Pathogenesis of regional enteritis, Ph-D-thesis, University of Minnesota, 1952.

  3. CHIODINI R.J., VAN KRUININGEN H.J., MERKAL R.S., THAYER W.R., CONTU J.A. — Characteristics of an unclassified Mycobacterium species isolated from patients with Crohn ’s disease.J. Clin. Microbiol., 1984 ; 20, 966- 971.

    PubMed  CAS  Google Scholar 

  4. JORGENSEN J.B. — An improved medium for culture of Mptbc from bovine faeces.Acta Vet. Scand., 1982, 23, 325–329.

    PubMed  CAS  Google Scholar 

  5. MC FADDE, J.J, HERMAN TAYLOR J.J. — Personal communications 1987, 1989 and 1990.

  6. CHIODINI R.J. — Crohn’ s Disease and the Mycobacterioses: a review and comparison of 2 disease entities.Clin. Microbiol. Rev., 1989, 2, 90–117.

    PubMed  CAS  Google Scholar 

  7. COLOE P, WILKS C.R, LIGHTFOOT D., TOSOLINI F.A. — Isolation of Mptbc in Crohn’s disease.Austral. Microbiol, 1986, 7, 188A.

    Google Scholar 

  8. GITNICK G., COLLINS J., BEAMAN B., BROOKS D., ARTHRU M., IMAEDA T., PALIESCHESKY M. — Preliminary report on isolation of Mycobacteria from patients with Crohn’s disease.Dig. Dis. Sci., 1989, 34, 925–935.

    Article  PubMed  CAS  Google Scholar 

  9. THOREL M.F. — Veterinary Institute Lyon. Personal communication 1989.

  10. GRAHAM D. — Oral Presentation 31-08-1990. World Congress of Gastroenterology Sydney.

  11. KREUZPAINTNER G., WALLNER A., KÖLBLE R. et al. — Spielen langsam wachsende Mykobacterien der Runyon gruppe III ätiologische eine Rolle bei M. Crohn. Zeitschrift fur Gastroenterologie 1989, 9, 494 A.

    Google Scholar 

  12. KOBAYASHI K., BLASER M.J., BROWN W.R. — Immunohistochemical examination for mycobacteria in intestinal tissue from patients with Crohn’s Disease.Gastroenterology, 1989, 96, 1009–1015.

    PubMed  CAS  Google Scholar 

  13. DAS P.K., BLAAUWGEERS J.L.S., SLOB A.W., SPIES J., CHAND A., KOLK A.H. — On the mycobacterial aetiology of Crohn’s Disease.Gastroenterol., 1988, 94, A88.

    Google Scholar 

  14. MOKRESH A.H., BUTTER D.G. — Granulomatous Enteritis Following Oral Inoculation of Newborn Rabbits with Mycobacterial Paratuberculosis of Bovine Origin.Can. J. Vet. Res., 1990, 54, 313–319.

    PubMed  CAS  Google Scholar 

  15. TYTGAT G.N.J., MULDER C.J.J. — The aetiology of Crohn’s Disease.Int. J. Colored Dig., 1986, 1, 188–192.

    Article  CAS  Google Scholar 

  16. BLAAUWGEERS H.L.L., MULDER C.J.J., DAS P.K., HAAGSMA J., TYTGAT G.N.J. — Crohn’s disease, a mycobacterial aetiology?Eur. J. Gastroenterol. Hepatol., 1990, 2, 237–240.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

About this article

Cite this article

Haagsma, J., Mulder, C.J.J., Eger, A. et al. Mycobacterium paratuberculosis isole chez des patients atteints de maladie de Crohn Résultats préliminaires. Acta Endosc 21, 255–260 (1991). https://doi.org/10.1007/BF02968714

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02968714

Mots-clés

Key-words

Palabras claves

Navigation