Abstract
Syringomatous adenoma of the nipple is a rare disease. To our knowledge, only 23 cases have been reported in the literature. We present the case of a 36-year-old lactating woman with syringomatous adenoma of the nipple, in whom local excision of the tumor was performed. Histologically, the tumor consisted of tubules, ductules and epithelial cell strands, and most of the proliferating ducts showed a characteristic teardrop or comma-shaped appearance. Careful monitoring to detect local recurrence is considered necessary, because syringomatous adenoma of the nipple, while being benign, is a locally invasive tumor.
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References
Rosen PP: Syringomatous adenoma of the nipple.Am J SurgPathol 7:739–745,1983.
Jones MW, Norris HJ, Snyder RC: Infiltrating syringomatous adenoma of the nipple: a clinical and pathological study of 11 cases.Am J Surg Pathol 13:197–201, 1989.
The Japanese Breast Cancer Society. General Rules for Clinical and Pathological Recording of Breast Cancer, 14th ed. Kanehara, Tokyo, pp19–56, 2000 (in Japanese).
Slaughter MS, Pomerantz RA, Murad T, Hines JR: Infiltrating syringomatous adenoma of the nipple.Surgery 111:711–713,1992.
Rosen PP, Ernsberger D: Low grade adenosquamous carcinoma: a variant of metaplastic mammary carcinoma.Am JSurgPathol 11:351–358,1987.
Ward BE, Cooper PH, Subramony C: Syringomatous tumor of the nipple.Am J Clin Pathol 92:692–696, 1989.
Rosen PP, Oberman HA: Syringomatous adenoma. In: Rosai J ed, Atlas of tumor pathology, 3rd series, fascicle 7. Armed Forces Institute of Pathology, Washington, DC, pp87–89,1993.
Cooper PH, Mills SE, Leonard DD, Santa Cruz DJ, Headington JT, Barr RJ, Katz DA: Sclerosing sweat duct (syringomatous) carcinoma.Am J Surg Pathol 9:422–433,1985.
Goldstein DJ, Barr RJ, Santa Cruz DJ: Microcystic adnexal carcinoma: a distinct clinicopathologic entity.Cancer 50:566–572,1982.
Toyoshima O, Kanou M, Kintaka N, Miyashita M, Shigematsu S, Sano J: Syringomatous adenoma of the nipple: Report of a case.Jpn J Surg 28:1196–1199, 1998.
Jones DB: Florid papillomatosis of the nipple ducts.Cancer 8:315–319,1955.
Sugai M, Murata K, Kimura N, Munakata H, Hada R, Kamata Y: Adenoma of the nipple in an adolescent.Breast Cancer 9:254–256, 2002.
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Kubo, M., Tsuji, H., Kunitomo, T. et al. Syringomatous adenoma of the nipple: A case report. Breast Cancer 11, 214–216 (2004). https://doi.org/10.1007/BF02968305
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DOI: https://doi.org/10.1007/BF02968305