Summary
It has been demonstrated that TCIII is present in pernicious anaemia (PA) multiple myeloma, chronic myeloid leukaemia (CML), polycythaemia vera (PV) and myelosclerosis. The levels of Transcobalmin I (TCI) and Trans-cobalamin III (TCIII) were increased in all disorders, except PA, in comparison with normal control sera. In CML both TCI and TCIII were greatly elevated, the former being elevated to a larger extent than the latter. The occurrence of TCIII in cord blood was also demonstrated.
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Bloomfield, F.J., Scott, J.M., Somerville, J.J.F. et al. Levels in normal, Pathological, and foetal sera of the three transcobalamins. Ir J Med Sci 142, 51–57 (1973). https://doi.org/10.1007/BF02949990
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DOI: https://doi.org/10.1007/BF02949990