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The effect of biotin on the production of succinic acid byAnaerobiospirillum succiniciproducens

  • Session 3 Bioprocessing Research
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Conclusion

The effect of biotin at 50 mg/L on the production of succinic acid byA. succiniciproducens has been studied. Biotin improved glucose consumption, cell growth, and succinic acid production. The specific productivity of succinic acid was improved by 16%. Biotin also increased the production of the byproduct acetic acid. The molar ratio of succinate:acetate was not changed by biotin.

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Authors and Affiliations

  1. Chemical Technology Division, Oak Ridge National Laboratory, MS-6226, PO Box 2008, 37831-6226, Oak Ridge, TN

    Nhuan P. Nghiem, Brian H. Davison, James E. Thompson, Bruce E. Suttle & Gerald R. Richardson

Authors
  1. Nhuan P. Nghiem
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  2. Brian H. Davison
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  3. James E. Thompson
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  4. Bruce E. Suttle
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  5. Gerald R. Richardson
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Additional information

The submitted manuscript has been authored by a contractor of the US government under contract No. DE-AC05-84OR21400. Accordingly, the US government retains a nonexclusive, royalty-free license to publish or reproduce the published form of this contribution, or allow others to do so, for US government purposes.

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Nghiem, N.P., Davison, B.H., Thompson, J.E. et al. The effect of biotin on the production of succinic acid byAnaerobiospirillum succiniciproducens . Appl Biochem Biotechnol 57, 633–638 (1996). https://doi.org/10.1007/BF02941744

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  • DOI: https://doi.org/10.1007/BF02941744

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