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Influence of the production of two lipopeptides, Iturin a and Surfactin S1, on oxygen transfer duringBacillus subtilis fermentation

  • Session 3 Bioprocessing Research
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Abstract

Bacillus subtilis produces three types of lipopeptides: Iturins, Fengycins, and Surfactins. These amphiphilic molecules influence the volumetric oxygen transfer (K L a) like chemical surfactant.K L a values were from two-to fivefold lower when both Iturin A and Surfactin S1 were coproduced, and from 0.57-to 0.8-fold lower when only Iturin A was produced. The addition of an oxygen vector (n-Dodecane) during fermentation increasedK L a values (7.5-fold) and biomass production (twofold), and decreased Iturin A and Surfactin S1 production. However, at high stirring conditions and in the presence ofn-Dodecane, Iturin A production was improved.

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References

  1. Peypoux, F., Guinand, M., Michel, G., Delcambe, L., Das, B. C., and Lederer, E. (1978),Biochemistry 17(19), 3992–3996.

    Article  CAS  Google Scholar 

  2. Vanittanakom, N., Loeffler, W., Koch, U., and Gunther, J. (1986),J. Antibiot. 39(7), 888–901.

    CAS  Google Scholar 

  3. Nichikiori, T., Naganawa, H., Muraoka, Y., Aoyagi, T., and Umezawa, H. (1986),J. Antibiot. 34(26), 775–761.

    Google Scholar 

  4. Arima, K., Kakinuma, A., and Tamura, G. (1968),Biochem. Biophys. Res. Commun. 31,3, 488–494.

    Article  Google Scholar 

  5. Peypoux, F., Pommier, M. T., Marion, P., Ptak, M., Das, B. C., and Michel, G. (1986),J. Antibiot. 39, 5.

    Google Scholar 

  6. Besson, F., Peypoux, F., Michel, G., and Delcambe, L. (1977),Eur. J. Biochem. 77, 61–67.

    Article  CAS  Google Scholar 

  7. Peypoux, F., Besson, F., Michel, G., and Delcambe, L. (1981),Eur. J. Biochem. 118, 323–327.

    Article  CAS  Google Scholar 

  8. Peypoux, F., Marion, D., Maget-Dana, R., Ptak, M., Das, B. C., and Michel, G. (1985),Eur. J. Biochem. 153, 335–340.

    Article  CAS  Google Scholar 

  9. Jacques, P., Hbid, C., Vanhentenryck, F., Destain, J., Baré, G., Razafindralambo, H., Paquot, M., and Thonart, P. (1993),Prog. Biotechnol. 9, 1067–1069.

    Google Scholar 

  10. Baumgart, F., Kluge, B., Ullrich, C., Vater, J., and Ziessow, D. (1991),Biochem. Biophys. Res. Commun. 177, 998–1005.

    Article  CAS  Google Scholar 

  11. Peypoux, F., Bonmatin, J. M., Labbé, H., Das, C. B., Ptak, M., and Michel, G. (1991),Eur. J. Biochem. 202, 101–106.

    Article  CAS  Google Scholar 

  12. Peypoux, F., Bonmatin, J. M., Labbé, H., Grangemard, I., Das, C. B., Ptak, M., and Michel, G. (1994),Eur. J. Biochem. 204, 89–96.

    Article  Google Scholar 

  13. Trischman, J. A., Jensen, P. R., and Fenical, W. (1994),Tetrahedron Lett. 35, 5571–5574.

    Article  CAS  Google Scholar 

  14. Thimon, L., Peypoux, F., Maget-Danat, R., and Michel, G. (1992),JAOCAS 9(1), 92,93.

    Article  Google Scholar 

  15. Maget-Dana, R., Thimon, L., Peypoux, F., and Ptak, M. (1992),J. Colloid. Interfac. Sci. 149(1), 174–183.

    Article  CAS  Google Scholar 

  16. Maget-Dana, R. and Ptak, M. (1992),J. Colloid. Interfac. Sci. 153(1), 285–291.

    Article  CAS  Google Scholar 

  17. Razafindralambo, H., Paquot, M., Hbid, C., Jacques, P., Destain, J., and Thonart, P. (1993),J. Chromatogr. 693, 81–85.

    Article  Google Scholar 

  18. Ohono, A., Ano, T., and Shoda, M. (1993),J. Ferment. Bioeng. 75(6), 463–465.

    Article  Google Scholar 

  19. Phae, C. G. and Shoda, M. (1991),J. Ferm. Bioeng. 71(2), 118–121.

    Article  CAS  Google Scholar 

  20. Aiba, S., Humphrey, A. E., and Millis, N. F. (1969),Biochemical Engineering. Academic, New York.

    Google Scholar 

  21. Rols, J. L., Condoret, J. S., Fonade, C., and Goma, G. (1990),Biotechnol. Bioeng. 35, 427–435.

    Article  CAS  Google Scholar 

  22. Chester, S. Ho., Lu-Kwang, J., and Raymond, F. B. (1990),Biotechnol. Bioeng. 36, 1110–1118.

    Article  Google Scholar 

  23. Jacques, P., Vanhentenryck, F., and Thonart, P. (1991),Arch. Int. Physiol. Bioch. 99, B62.

    Google Scholar 

  24. Cooper, D. G., Macdonald, C. R., Duff, S. J., and Kosaric, N. (1981),Appl. Environ. Microbiol. 42(3), 408–412.

    CAS  Google Scholar 

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Hbid, C., Jacques, P., Razafindralambo, H. et al. Influence of the production of two lipopeptides, Iturin a and Surfactin S1, on oxygen transfer duringBacillus subtilis fermentation. Appl Biochem Biotechnol 57, 571–579 (1996). https://doi.org/10.1007/BF02941737

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