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Pharmacological activity of the Samoan ethnopharmacopoeia

’O le aoga fa’availa’au o vai Samoa

Actividad farmacológica de la etnofarmacopea Samoana

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Abstract

The Samoan ethnopharmacopoeia was surveyed for pharmacological activity using broad in vitro and in vivo screens. Residues of 74 different plant species were tested for activity in a Hippocratic screen and in a guinea pig ileum test. Over 86% of the plant species exhibited pharmacological activity. This high percentage of active species strongly supports the belief that ethnobotanical analyses of indigenous floras are more likely than random screens to efficiently identify plants likely to yield new drugs. However, collaboration of ethnobotanists and pharmacognosists is necessary to adequately move promising plants from the realm of indigenous knowledge systems to the laboratories of Western pharmacology.

Abstract

Sa su’esu’e lava la’au e fai vai Samoa mo a latou aoga fa’afoma’i i ni auala se lua fa’asaienisi: o le in vitropo’o le su’esu’ega i mea ua tipi ’ese mai manu ma le in vivo po’o le su’esu’ega i manu olo’o ola lava. Sa tofutofu ai la’au ’ese’ese e 74 i na auala se lua. Sa matou fa’atonu ai le aoga i le sili atu i le 86% o na la’au. O lena pesene maualuga e matua’i fa’amaoni ai le aoga o le a’oa’oina o le faiga o vai o atunu’u ’ese’ese ma le fa’atauva’aina o su’esu’ega mo la’au e aunoa ma le amana’ina o le poto o tagata fa’aleatunu’u. E tatau lava ona galulue gatasi ai tagata su’e le faiga vai (ethnobotanists) ma tagata su’e vai la’au (pharmacognosists) ina ia maua ai la’au fou e aoga ai mo tagata gasegase.

Résumé

Se analizó la etnofarmacopea de Samoa para la actividad farmacológica usando amplias pruebas in vitro e in vivo. Se probaron los residuos de 74 diferentes especies de plantas para la actividad en una prueba hipocrática y en una prueba de “guinea pig.” Más del 86% de las especies de plantas mostraron actividad farmacológica. Este alto porcentage de especies activas confirma ampliamente la creéncia de que los análisis etnobotánicos de floras indígenas son más factibles que las pruebas al azar, para identificar más eficientemente a plantas que produzcan nuevas drogas. Sin embargo, la colaboración de etnobotánicos y farmacognosistos es necesaria para extraer las plantas del campo de conocimiento indígena hacia los laboratories farmacológicos del oeste.

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Cox, P.A., Sperry, L.R., Tuominen, M. et al. Pharmacological activity of the Samoan ethnopharmacopoeia. Econ Bot 43, 487–497 (1989). https://doi.org/10.1007/BF02935923

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