Abstract
Familial adenomatous polyposis of the colon, or Gardner's syndrome, is often accompanied by adenomas of the stomach and duodenum. We experienced a rare case of Gardner's syndrome, with adenomas of the common bile duct, in a patient who presented with relapsing acute pancreatitis. Our findings indicate that adenoma in the common bile duct or pancreatic duct should be considered as a possible etiology when patients with familial polyposis or Gardner's syndrome present with pancreatitis, particularly relapsing acute pancreatitis.
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Iida M, Yao T, Itoh H, et al. Natural history of duodenal lesions in Jananese patients with familial adenomatosis coli (Gardner's syndrome). Gastroenterology 1989;96:1301–1306.
Erwald R. Gardner's syndrome with adenoma of the common bile duct. Acta Chir Scand Suppl 1984;520:63–68.
Shemesh E. Adenomatous polyp of the common bile duct in familial polyposis coli. Israel J Med Sci 1985;21:701–702.
Burt RW, Rikkers LF, Gardner EJ, et al. Villous adenoma of the duodenal papilla presenting as necrotizing pancreatitis in a patient with Gardner's syndrome. Gastroenterology 1987;92:532–535.
Stevenson JK, Reid BJ. Unfamiliar aspects of familial polyposis coli. Am J Surg 1986;152:81–86.
Perzin KH, Bridge MF. Adenomas of the small intestine: A clinicopathologic review of 51 cases and a study of their relationship to carcinoma. Cancer 1981;48:799–819.
Reddy RR, Schuman BM, Priest RJ. Duodenal polyps: Diagnosis and management. J Clin Gastroenterol 1981;3:139–145.
Yao T, Iida M, Ohsato K, et al. Duodenal lesions in familial polyposis of the colon. Gastroenterology 1977;73:1086–1092.
Järvinen H, Nyberg M, Peltokallio P. Upper gastrointestinal tract polyps in familial adenomatosis coli. Gut 1983;24:333–339.
Bülow S, Lauritsen KB, Johansen A, et al. Gastroduodenal polyps in familial polyposis coli. Dis Colon Rectum 1985;28:90–93.
Jagelman DG, DeCosse JJ, Bussey HJR. Upper gastrointestinal cancer in familial adenomatous polyposis. Lancet 1988;I:1149–1151.
Offerhaus GJA, Giardiello FM, Krush AJ, et al. The risk of upper gastrointestinal cancer in familial adenomatous polyposis. Gastroenterology 1992;102:1980–1982.
Arvanitis ML, Jagelman DG, Fazio VW, et al. Mortality in patients with familial adenomatous polyposis. Dis Colon Rectum 1990;33:639–642.
Pauli RM, Pauli ME, Hall JG. Gardner syndrome and periampullary malignancy. Am J Med Genet 1980;6:205–219.
Berk T, Friedman LS, Goldstein SD, et al. Relapsing acute pancreatitis as the presenting manifestation of an ampullary neoplasm in a patient with familial polyposis coli. Am J Gastroenterol 1985;80:627–629.
Clarke DN, Norman JN, Smith JAR, et al. Pancreatitis and duodenal obstruction due to periampullary carcinoma associated with familial polyposis coli. Postgrad Med J 1987;54:418–420.
Komorowski RA, Tresp MG, Wilson SD. Pancreaticobiliary involvement in familial polyposis coli/Gardner/s syndrome. Dis Colon Rectum 1986;29:55–58.
Spigelman AD, Farmer KCR, James M, et al. Tumours of the liver, bile ducts, pancreas and duodenum in a single patient with familial adenomatous polyposis. Br J Surg 1991;78:979–980.
Opie EL. The etiology of acute hemorrhagic pancreatitis. Johns Hopkins Hosp Bull 1901;12:182–188.
Elliot DW, Williams RD, Zollinger RM. Alterations in pancreatic resistance to bile in the pathogenesis of acute pancreatitis. Ann Surg 1957;146:669–682.
Robinson TM, Dunphy JE. Continuous perfusion of bile protease through the pancreas. JAMA 1963;183:530–533.
White TT, Magee DF. Perfusion of the dog pancrease with bile without producing pancreatitis. Ann Surg 1960;131:245–250.
Lerch MM, Weidenbach H, Hernandez CA, et al. Pancreatic outflow obstruction as the critical event for human gall stone induced pancreatitis. Gut 1994;35:1501–1503.
Ryan DP, Schapiro RH, Warshaw AL. Villous tumors of the duodenum. Ann Surg 1986;203:301–306.
Cooperman M, Clausen KP, Hecht C, et al. Villous adenomas of the duodenum. Gastroenterology 1978;74:1295–1297.
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Futami, H., Fututa, T., Hanai, H. et al. Adenoma of the common bile duct in Gardner's syndrome may cause relapsing acute pancreatitis. J Gastroenterol 32, 558–561 (1997). https://doi.org/10.1007/BF02934100
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DOI: https://doi.org/10.1007/BF02934100