Abstract
The extraction of panaxynol and panaxydol from Korean ginseng was found to be optimal at 55°C for the shaking method, 80°C for the soxhlet method, and 65°C for the supercritical extraction method. The amount of extracted panaxydol and panaxynol, and their ratio increased over a period of 12h with the shaking method. The soxhlet method produced an extract with the largest panaxydol/panaxynol ratio. A reduced particle size enhanced extraction, however, the ratio of panaxydol/panaxynol decreased. Swelling in water was found to be detrimental for the extraction of panaxydol and panaxynol.
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References
Hahn, D. R. (1978) Pharmaco-biological of the ginsenosides Rb1, Rg1 and Re.Proceedings of the 2nd International Symposium on Ginseng. p. 135. September 7–11. Korea.
Takagi, K. (1974) Pharmacological studies on ginseng.Proceedings of the 1st International Symposium on Ginseng. p. 119. September 7–11. Korea.
Yamamoto, M., Y. Hayashi, and A Kumagai (1980) Lipid metabolism and several saponin principles.Proceedings of the 3rd International Symposium on Ginseng. p. 115. September 8–10. Korea.
Odashima, S., Y. Nakayabu, N. Honjo and S. Arichi (1979) Induction of phenotypic reverse transformation by ginsenosides in cultured Morris hepatimacells.Eur. J. Cancer 15: 885–892.
Ahn, P. Z., S. I. Kim, K. S. Kang, and Y. S. Kim (1988) the action of cytotoxic components of Korean ginseng against L1210 cells and their structure-activity relationship.Proceedings of the 5th International Symposium on Ginseng. pp. 19–24. August 29–September 1. Korea.
Hirakura, K., M. Morita, K. Nakajima, Y. Ikeya, and H. Mitsuhashi (1982) Three acetylenic compounds from roots ofPanax ginseng.Phytochemistry 31: 899–903.
Matsunaga, H., M. Katano, H. Yamamoto, H. Fujito, M. Mori and T. Takata (1990) Cytotoxic activity of polyacetylene compounds inPanax ginseng.Chem. Pharm. Bull. 38: 3480–3482.
Kitagawa, I. (1983) Comparison of the components between red and white ginseng discovery of biologically active substance, ginsenoside Rh2, from red ginseng.The Ginseng Review 1: 21–29.
Takahashi, M., K. Isoi, Y. Kimura, and M. Yoshikura (1964) Studies on the components ofPanax ginseng C. A. Meyer.J. Pharm. Soc. Japan 84: 757–759.
Shim, S. C., S. K. Chang, C. W. Hur, and C. K. Kim (1987) A polyacetylenic compound fromPanax ginseng roots.Phytochemistry 26: 2849–2850.
Kim, S. I. (1988)Studies on the Cytotoxic Components of the Korean Ginseng Roots. Ph. D. Thesis. Chungnam National University, Taejon, Korea.
Boll, P. M. and L. Hansen (1987) On the presence of falcarinol in araliaceae.Phytochemistry 26: 2955–2956.
Fujimoto, Y. and M. Satoh (1987) Acetylenes from the callus ofPanax Ginseng.Phytochemistry 26: 2850–2852.
Nho, K. B. and H. J. Sohn (1989) Comparative studies on methods of extracting polyacetylene compounds from white ginseng.Kor. J. Ginseng Sci. 13: 183–188.
Yoo, B. S., H. J. Lee, S. R. Ko, D. C. Yang, and S. Y. Byun (2000) Studies on the extraction of polyacetylene from Korean ginseng using supercritical carbon dioxide.Kor. J. Biotechnol. Bioeng. 15: 80–83.
Nho, K. B. and H. J. Sohn (1989) Determination of the concentration of panaxynol, panaxydol and panaxytriol by Capillary-GC(FID).Kor. J. Ginseng Sci. 13: 198–201.
McCabe, W. L., J. C. Smith, and P. Harriott (1993)Unit Operations of Chemical Engineering, 5th ed., pp. 1108–1109. McGraw-Hill, USA.
Sung, H. S., C. B. Yang, and W. J. Kim (1985) Effect of extraction temperature and time on saponin composition of red ginseng extract.Kor. J. Food Sci. Technol. 17: 241–246.
Clifford, A. A. (1994)Reaction in Supercritical Fluids. p. 449. Kluwer Academic Publishers, Netherlands.
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Park, CE., Baek, NI. & Park, CH. Extraction of panaxynol and panaxydol compounds from Korean ginseng. Biotechnol. Bioprocess Eng. 6, 433–437 (2001). https://doi.org/10.1007/BF02932325
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DOI: https://doi.org/10.1007/BF02932325