Abstract
Sera of 112 healthy Hungarian blood donors were tested for the presence ofYersinia enterocolitica andY. pseudotuberculosis-specific agglutinins by tube agglutination, and for that of yersinia outer membrane protein (Yop)-specific IgA antibodies by ELISA. The positive results of this latter assay were confirmed by immunoblot. Only one sample gave a positive agglutination reaction withY. enterocolitica antigen (group O3) and four exhibited an equivocal reaction withY. pseudotuberculosis antigens (groups II and IV). Contrary to the low incidence of agglutinins, 15.1% of the samples showed a positive Yop-specific IgA reaction, while further 5.3% samples fell into the equivocal range by ELISA (17 and 6 specimens, respectively). Eleven of these samples (9.8% of all specimens tested) were also positive by immunoblot for the presence of Yop-specific IgA antibodies. These data suggest a higher incidence of yersinia infections than the 1.0–1.4 per 105 population predicted on the basis of stool culture results.
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Sonnevend, Á., Czirók, É. & Pál, T. Yersinia Yop-Specific IgA antibodies in Hungarian blood donors. Folia Microbiol 50, 269–272 (2005). https://doi.org/10.1007/BF02931576
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DOI: https://doi.org/10.1007/BF02931576