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Nondispersive extraction for recovering lactic acid

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Abstract

A nondispersive extraction process for recovery of lactic acid from fermentation broth is being developed. The criteria for selection of solvent, distribution of lactic acid between the aqueous and solvent phases, and the effect of presence of other compounds in the broth, are discussed. Working with a simulated fermentation broth (without cells), a hydrophobic membrane module has been evaluated for its effectiveness as extractor. Back extraction and its role has been demonstrated. A theoretical comparison of this process with electrodialysis shows membrane extraction to be more desirable.

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Abbreviations

ad :

Specific surface area of alkali droplets, cm2/cm3

Ao :

Mass transfer surface area in membrane module, m2

Ac :

Total cross-sectional area of fiber tubes, cm2

C1 :

Concentration of lactic acid in the inlet solvent stream to extractor, g/L

C2 :

Concentration of lactic acid in the outlet solvent stream from extractor, g/L

do :

Outside diameter of membrane fibers, cm

dp :

Average diameter of membrane fibers, cm

FB :

Volumetric flow rate of broth, L/h

Fs :

Volumetric flow rate of solvent, L/h

kc :

Mass transfer coefficient between solvent and alkali phase in the solvent tank, cm/s

kc :

Mass transfer coefficient between solvent and alkali phase in the fiber tubes, cm/s

ko :

Over-all mass transfer coefficient across the membrane in the extractor, cm/s

m:

Distribution coefficient, dimensionless

m' :

Distribution coefficient of lactic acid at the pH of alkali solution, dimensionless

m* :

Partition coefficient of lactic acid, dimensionless

P1 :

Concentration of lactic acid in the inlet aqueous stream to extractor, g/L

P2 :

Concentration of lactic acid in the outlet aqueous stream from extractor, g/L

Pa :

Concentration of lactic acid in alkali phase, g/L

VI :

Volume of aqueous phase, L

VII :

Volume of solvent (TOPO+kerosene) phase, L

VIII :

Volume of alkali phase emulsified in the solvent, L

ØD :

Volume fraction of alkali in the solvent emulsion, L

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Authors and Affiliations

  1. Departments of Chemical Engineering, University of Missouri-Columbia, 65211, Columbia, MO

    C. J. Wang & R. K. Bajpai

  2. Agricultural Engineering, University of Missouri-Columbia, 65211, Columbia, MO

    E. L. Iannotti

Authors
  1. C. J. Wang
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  2. R. K. Bajpai
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  3. E. L. Iannotti
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Wang, C.J., Bajpai, R.K. & Iannotti, E.L. Nondispersive extraction for recovering lactic acid. Appl Biochem Biotechnol 28, 589–603 (1991). https://doi.org/10.1007/BF02922635

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