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Comparative study of methods for determining lanthanide elements in biological materials by using NAA, HPLC postcolumn reaction, and ICP-MS

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Abstract

Mice were injected intravenously with one of the following elements: Y, La, Ce, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, or Yb, at a dose of 25 mg/kg body wt. After 20 h, the various organs were taken out, and the element concentrations were determined by NAA, HPLC postcolumn reaction, or ICP-MS. The results by these three methods were within the acceptable range. About 85% of the amount administered of each element was found in liver, lung, and spleen.

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Authors and Affiliations

  1. Juntendo University School of Medicine, 113, Tokyo, Japan

    Momoko Chiba, Atsuko Shinohara & Yutaka Inaba

  2. Nuclear and Energy Research Institute, São Paulo, Brazil

    Mitiko Saiki

Authors
  1. Momoko Chiba
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  2. Atsuko Shinohara
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  3. Mitiko Saiki
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  4. Yutaka Inaba
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Chiba, M., Shinohara, A., Saiki, M. et al. Comparative study of methods for determining lanthanide elements in biological materials by using NAA, HPLC postcolumn reaction, and ICP-MS. Biol Trace Elem Res 43, 561–569 (1994). https://doi.org/10.1007/BF02917359

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  • DOI: https://doi.org/10.1007/BF02917359

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