Abstract
The epidemiological relationship between selenium level and age-adjusted human cancer mortality (incidence) was studied in 24 regions located in eight provinces of China. Statistically significant inverse correlation was found between age-adjusted total cancer death rates and selenium levels in whole blood from local residents. In the areas with high selenium levels, there was significantly lower mortality in both males and females from cancer of the stomach and esophagus. In addition, an inverse correlation between regional distribution of liver cancer incidence and selenium contents in blood and grains in Qidong county, an area with high risk of hepatoma, was observed. With the intention of providing selenium supplements to residents living in low selenium regions, the selenium content in grains was raised by means of foliar spraying of crops with Na2SeO3 solution.
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Yu, SY., Chu, YJ., Gong, XL. et al. Regional variation of cancer mortality incidence and its relation to selenium levels in China. Biol Trace Elem Res 7, 21–29 (1985). https://doi.org/10.1007/BF02916544
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DOI: https://doi.org/10.1007/BF02916544
Index Entries
- Selenium, cancer mortality correlation
- cancer mortality, stomach, esophagus, liver, inverse associatioin with blood selenium level
- selenium, in high risk areas for liver cancer
- China, selenium and cancer distribution in
- selenium supplementation, enrichment of selenium in grains
- foliar spraying with selenite, of grains
- stomach cancer mortality rate, and selenium in China
- esophageal cancer mortality rate, and selenium in China
- liver cancer mortality rate, and selenium in China