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Enzymatic labeling of nucleic acids

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Abstract

Enzymatic labeling of nucleic acids is a fundamental tool in molecular biology with virtually every aspect of nucleic acid hybridization technique involving the use of labeled probes. Different methods for enzymatic labeling of DNA, RNA and oligonucleotide probes are available today. In this review, we will describe both radioactive and nonradioactive labeling methods, yet the choice of system for labeling the probe depends on the application under study.

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  1. Hybridon, Inc., One Innovation Dr, 01605, Worcester, MA

    Jamal Temsamani & Sudhir Agrawal

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  1. Jamal Temsamani
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  2. Sudhir Agrawal
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Temsamani, J., Agrawal, S. Enzymatic labeling of nucleic acids. Mol Biotechnol 5, 223–232 (1996). https://doi.org/10.1007/BF02900360

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