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Alterations of serum cholesterol and serum lipoprotein in breast cancer of women

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Abstract

Fasting blood sample of 50 normal subjects (control) and 100 patients of breast cancer were investigated for serum total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, very low density lipoprotein, high density lipoprotein cholesterol:low density lipoprotein cholesterol ratio and total cholesterol:high density lipoprotein cholesterol ratio during breast cancer of women. Five cancer stages, types, age groups, parity and menopausal status were undertaken for the study. It was observed that there was a significant rise in serum total cholesterol and low density lipoprotein cholesterol whereas high density lipoprotein cholesterol and very low density lipoprotein cholesterol were not significant. The ratio of high density lipoprotein cholesterol:low density lipoprotein cholesterol and total cholesterol:high density lipoprotein cholesterol values increased significantly in breast cancer patients.

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Bibliography

  1. Bani I.A., Williams, C.M., Boulter P.S., Dickerson J.W.T., (1986). Plasma lipids and prolactin in patients with breast cancer. Br. J. Cancer, 54: 439–446.

    PubMed  CAS  Google Scholar 

  2. Knapp M.L., Al Sheibani S., Richer P.G., (1991). Alteration of serum lipids in breast cancer. Effect of disease activity treatment and hormonal factor. Clin Chem: 37: 2093–2101.

    PubMed  CAS  Google Scholar 

  3. Kumar K. Sachdanandam P., (1991). Studies on the changes in plasma lipids, lipoproteins in patients with benign and malignant breast cancer. Biochem. Inter. 23: 581–589.

    CAS  Google Scholar 

  4. Zielinski C.C., Stuller I, Rausch P, Muller C., (1988). Increased serum concentration of cholesterol and triglycerides in the progression of breast cancer. J. Cancer. Res. Clin. Oncol. 114; 514–518.

    Article  PubMed  CAS  Google Scholar 

  5. Boyd N.F. Mc Guine V., (1990). Evidence of association between plasma high density lipoprotein cholesterol and risk factor of breast cancer. J. Natl. Cancer Inst. 82; 460–468.

    Article  PubMed  CAS  Google Scholar 

  6. Goodwin P.G. Boyd N.F., (1988). Mammographic parenchymal pattern and breast cancer risk. A critical appraisal the evidence. Anij. Epidemiol 127: 1097–1108.

    CAS  Google Scholar 

  7. Roosner, S. Wallgren A., (1984). Serum lipoprotein and protein after breast cancer surgery and effects of tamoxifen. Atherosclerosis. 52; 336–346.

    Google Scholar 

  8. Agheli, N.; Therwath, A. (1994). Nutrition dietary factors and breast cancer. A Review—Indian Journal of Cancer 31: 218–285.

    PubMed  CAS  Google Scholar 

  9. Ray, G.; Hussain, S.A. (2001). Role of lipid, lipoprotein and vitamins in women with breast cancer. Clin Biochem. 34: 71–76.

    Article  PubMed  CAS  Google Scholar 

  10. Florenza Am, Branchi A., Sommaviva D., (2000). Serum lipoprotein profile in patients with cancer. A comparison with non-cancer subjects. Int J Clin Lab Res, 2000; 30; 141–145.

    Article  Google Scholar 

  11. Corinne H. Robbinson, Marilyn; Lawley, R. (1982). Lipids metabolism and dietary fats, normal and therapeutic nutrition 16th Edition. 105–109.

  12. Wybenga D.R. Pileggi, B.J.; Dirstina T.H.; DiGiogio, J. (1970). Direct mannual determination of serum total cholesterol with a single stable reagent. Clin Chem. 16, 980–984.

    PubMed  CAS  Google Scholar 

  13. Lane, D.M.; Boatman K.K.; McCarthy, W.J. (1995). Serum lipids and lipoproteins in women with breast masses. Breast Cancer Res Treat; 34: 161–9.

    Article  PubMed  CAS  Google Scholar 

  14. Mady EA, (2000). Association between estradiol, estrogen receptors, total lipids, triglycerides and cholesterol in patient with benign and malignant breast tumors. J. Steroid. Biochem. Mol. Biol; 75: 323–328.

    Article  PubMed  CAS  Google Scholar 

  15. Ray A, Jain D, Yadav R, Naik S.L. Sharma S, Bhadur A.K. Sharma B.K. (2001). Effect of cancer treatment modalities on serum lipid and lipoprotein among women with carcinoma of breast. Indian J. Physiol Pharmacol; 45 337–44.

    PubMed  CAS  Google Scholar 

  16. Kokuglu E, Karaarslan I, Karaarslan HM, Baloglu H., (1994). Alteration of serum lipids and lipoproteins in breast cancer. Cancer Lett; 82: 175–8.

    Article  Google Scholar 

  17. Hoyer AP, Engholon G., (1992). Serum lipids and breast cancer risk: A cohort study of 5,207 Danish women. Cancer Causes Control 3: 403–8.

    Article  PubMed  CAS  Google Scholar 

  18. Elkhadrawy T.M. Ahsan H, Neugut AI, (1998). Serum cholesterol and risk of ductal carcinoma in situ: a case control study. Eur. J. Cancer Prev. 7: 393–396.

    Article  PubMed  CAS  Google Scholar 

  19. Brinton, Machmohan B, Cole P Lin T., (1970). Age at 1st child birth Br. Ca. Risk WHO. 1070: 43–209.

    Google Scholar 

  20. Tornberg S.A., Holm L.E., Carstensen J.M. (1988). Breast cancer risk in relation to serum cholesterol, serum beta lipoprotein, height, weight and blood pressure. Acta Oncol. 27: 31–7.

    Article  PubMed  CAS  Google Scholar 

  21. Schreier Le, Breg Ga, Basilio F.M., Lopez GI, Etkin AE, Wikinski RL, (1999). Lipoprotein alteration, abdominal fat distribution and breast cancer. Biochem Mol Biol Int 44: 681–690.

    Google Scholar 

  22. Kannel WB. (1987) Status of risk factors and their consideration in antihypertensive therapy. Am J Cardiol; 59: 80A-90A.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Dept of Biochemistry, NSCB Medical College, 482 003, Jabalpur

    Kiran Hasija & Hardeep K. Bagga

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  1. Kiran Hasija
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  2. Hardeep K. Bagga
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Correspondence to Kiran Hasija.

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Hasija, K., Bagga, H.K. Alterations of serum cholesterol and serum lipoprotein in breast cancer of women. Indian J Clin Biochem 20, 61–66 (2005). https://doi.org/10.1007/BF02893044

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