Summary
In order to investigate the susceptibility of mixed infection ofUreaplasma Urealyticum (UU) andMycoplasma Hominis (MH) to 7 kinds of antimicrobial agents and comparison with that of UU infection in NGU patients, thein vitro susceptibility was determined by using microdilution method. The positive results were analyzed. The results showed that the sequence of susceptibility to 7 kinds of antimicrobial agents for both UU infection group and UU-MH mixed infection group was almost the same from the highest susceptibility to the lowest accordingly: Josamycin, Doxycycline, Minocycline, Sparfloxacin, Roxithromycin, Ofloxacin and Azithromycin. The total drug resistance rate for UU-MH mixed infection group (97.67%) was significantly higher than that for UU infection group (44.67%,P<0.01). The highest drug resistance rate in UU group and UU-MH mixed infection group was 31.33% (Ofloxacin) and 90.48% (Azithromycin) respectively. UU-MH mixed infection showed an increased drug resistance and changes of drug resistance spectrum.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Limb D I. Mycoplasmas of the human genital tract. J Med Lab Science, 1989, 46:146
Oggini M R, Dowson C G, Smith J Met al. The tetracycline resistance gene tet(M) exhibits mosaic structure. Plasmid, 1996,35:156
Author information
Authors and Affiliations
Additional information
HUANG Chengzheng, male, born in 1964, Doctor in Charge
Rights and permissions
About this article
Cite this article
Changzheng, H., Zhixiang, L., Nengxing, L. et al. Susceptibility of mixed infection ofUreaplasma urealyticum andMycoplasma hominis to seven antimicrobial agents and comparison with that ofUreaplasma urealyticum infection. Current Medical Science 23, 203–205 (2003). https://doi.org/10.1007/BF02859959
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02859959