Abstract
Betulin, which is a medicinal pentacyclic triterpene, is abundant in the bark of white birch (Betula platyphlly). The bark of birch was collected at Tayuan Forest Farm of Jiagedaqi, Heilongjian Province in September 2000. Supercritical fluid extraction (SFE) that is a new separation technology has been used for the processing pharmaceutical and natural products. In this paper, the extraction of betulin from the bark of birch by supercritical CO2 extraction was studied. The authors investigated and analyzed a few parameters such as modifier dosage, extraction pressure and extraction temperature. The optimal extraction conditions showed that the modifier dosage used for per gram bark powder was 1.5 mL, the extraction pressure was at 20 Mpa, and the extraction temperature was at 55 °C. The velocity of flow of liquid CO2 was at 10 kg/h. The pressure and temperature in separation vessel were at 5.5 Mpa and 50 °C, respectively.
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Foundation item: This paper was supported by Natural Science Foundation of Heilongjiang.
Biography: ZHANG Yu-hong (1972-), male, Lecturer in Northeast Forestry University, Harbin 150040, P. R. China
Responsible editor: Zhu Hong
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Yu-hong, Z., Tao, Y. & Yang, W. Extraction of betulin from bark ofBetula platyphylla by supercritical carbon dioxide extraction. Journal of Forestry Research 14, 202–204 (2003). https://doi.org/10.1007/BF02856830
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DOI: https://doi.org/10.1007/BF02856830