Abstract
Softgels, which contain a liquid formulation of a drug, often provide clinical benefit over other solid oral dosage forms and may represent an attractive alternative to them. A consumer preference survey of softgels versus other solid forms investigated four areas: (1) identification of various dosage forms; (2) perception of therapeutic benefit (easiest to swallow, faster-acting, work longer); (3) impact of individual product characteristics on overall product selection; and (4) market impact in terms of premiums consumers would pay on the basis of dosage form. The 300 survey participants strongly preferred clear softgels over other dosage forms in virtually every area. Softgels were perceived as easy to swallow and fast-acting, with a duration of action second only to that of a two-piece capsule. Overall preference was driven by ease of swallowing, and softgels were rated first by the majority of respondents. Consumers would be interested in various products if these were available as softgels rather than in their current oral dosage forms and may be willing to pay a premium for softgel products. This survey confirms consumer preferences for particular dosage forms and for softgels over other solid forms. Pharmaceutical scientists and marketers should consider softgels as alternative dosage forms when developing new compounds or considering life-cycle management of existing products.
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Patel AG, Gura R, Kurian T, et al. A comparison of the hypnotic effects of temazepam capsules and temazepam elixir.Int Clin Psychopharmacol. 1991;6:1–9.
Mitsuyasu RT, Skolnik PR, Cohen SR, et al. Activity of the soft gelatin formulation of saquinavir in combination therapy in antiretroviral-naïve patients.AIDS. 1998;12:F103-F109.
Erb R, Stoltman W. Evaluation of two nitroglycerin dosage forms: a metered spray and a soft gelatin capsule.J Pharmacokinet Biopharm. 1983;11:611–621.
Astorri E, Bianchi G, La Canna G, et al. Bioavailability and related heart function index of digoxin capsules and tables in cardiac patients.J Pharm Sci. 1979;68:104–106.
Bateman NE, Uccellini DA. Effect of formulation on the bioavailability of retinol, D-alpha-tocopherol and riboflavine.J Pharm Pharmacol. 1984;36:41–46.
Saano V, Paronen P, Peura P, Vidgren M. Relative pharmacokinetics of three oral 400 mg ibuprofen dosage forms in healthy volunteers,Int J Clin Pharmacol Ther Toxicol. 1991;29:381–385.
Hong SS, Lee SH, Lee YJ, et al. Accelerated oral absorption of gliclazide in human subjects from a soft gelatin capsule containing a PEG 400 suspension of gliclazide.J Controlled Release. 1998:51:195–192.
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Jones, W.J., Francis, J.J. Softgels: Consumer perceptions and market impact relative to other oral dosage forms. Adv Therapy 17, 213–221 (2000). https://doi.org/10.1007/BF02853160
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DOI: https://doi.org/10.1007/BF02853160