Skip to main content
Log in

Effect of a probiotic multivitamin compound on stress and exhaustion

  • Published:
Advances in Therapy Aims and scope Submit manuscript

Abstract

This 6-month study evaluated a probiotic multivitamin preparation in 42 adult men and women suffering from stress or exhaustion. The preparation was taken daily with breakfast. A psychological-neurologic questionnaire assessed psycho-organic, central vegetative, and somatic discomforts, and a validated list of adjectives was used to indicate the effect of therapy. At the end of the study, an overall 40.7% improvement in stress was noted, representing significant improvements of 17.4% in positive conditions and of 23.3% in negative conditions (both P<.001). In addition, decreases of 29% in the frequency of infections and of 91% in gastrointestinal discomforts, both established indicators of stress, were recorded. The preparation was well tolerated. This probiotic multivitamin is suitable for reducing stress or exhaustion, or both, as well as for improving the immune system, specifically gastrointestinal health.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Bullinger M. Befindlichkeitsstörungen. In:Handbuch der Umweltmedizin. Landsberg: Ecomed; 1992:1–11.

    Google Scholar 

  2. Evans DL, Leserman J, Pedersen CA, et al. Immune correlates of stress and depression.Psychopharmacol Bull. 1989;25:319–324.

    PubMed  CAS  Google Scholar 

  3. Irwin M, Patterson MT, Smith TL, et al. Reduction of immune function in life stress and depression.Biol Psychiatry. 1990;27:22–30.

    Article  PubMed  CAS  Google Scholar 

  4. Csef H, Kraus MR. Zeiterleben, Stress und Krankheitsentstehung.Therapiewoche. 1996;46: 269–275.

    Google Scholar 

  5. Siegrist J. Der Einfluss sozialer Faktoren auf die Entstehung chronischer Erkrangungen am Beispiel ischämischer Herzkrankheiten.Internist. 1984;25:659–666.

    PubMed  CAS  Google Scholar 

  6. Kelly GS. Nutritional and botanical interventions to assist with the adaption to stress.Altern Med Rev. 1999;4:249–265.

    PubMed  CAS  Google Scholar 

  7. Ussher JM, Dewberry C, Malson H, Noakes J. The relationship between health related quality of life and dietary supplementation in British middle managers: a double-blind placebo-controlled study.Psychol Health. 1995;10:97–111.

    Article  Google Scholar 

  8. Schneider H, Wall H, Zeller HJ. Der psychologisch-Neurologische-Fragebogen—ein Screeningverfahren bei Tauglichkeits- und Überwachungsuntersuchungen.Z Klin Med. 1988; 43:1321–1322.

    Google Scholar 

  9. Janke W, Debus G.Die Eigenschaftswörterliste (EWL), Handanweisung. Göttingen: Verlag der Psychologie; 1978.

    Google Scholar 

  10. Brickenkamp H.Handbuch psychologischer Test. Göttingen: Hogrefe Verlag; 1997:536.

    Google Scholar 

  11. Janke W, Hüppe E. Emotionalität. In: Oswald WD, Herrmann WM, Kanowsk S, Lehr WM, Thomae H, eds.Lehrbuch er Gerontologie. Stuttgart: Kohlhammer Verlag; 1991:88–124.

    Google Scholar 

  12. Biesalski HK, Grimm P.Taschenatlas der Ernährung. Stuttgart: Thieme-Verlag; 1999.

    Google Scholar 

  13. Deutsche Gesellschaft für Ernährung (DGE). Verbessern Prä- und Pribiotika de Gesundheit? Ergebnisse des Ernährungsberichts 2000 der DGE. Pressinformation der DGE; January 2001.

  14. Anderson RA, Roussel A-M, Zouari N, Mahjoub S, Matheau J-M, Kerkeni A. Potential antioxidant effects of zinc and chromium supplementation in people with type II diabetes mellitus.J Am Coll Nutr. 2001;20:212S-218S.

    Google Scholar 

  15. Biesalski HK. Antioxidative Vitamine in der Arterioslerose-Prävention: Vitamin-E-Zufuhr statt lipidsender Therapei?Therapiewoche. 1992;42:2168–2180.

    Google Scholar 

  16. Biesalski HK. Vitamine in der Prävention von Krebserkrankungen.Münch Med Wochenschr. 1996;138:315–320.

    Google Scholar 

  17. Ruhe RC, McDonald RB. Use of antioxidant nutrients in the prevention and treatment of type II diabetes.J Am Coll Nutr. 2001;20:363S-369S.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gruenwald, J., Graubaum, HJ. & Harde, A. Effect of a probiotic multivitamin compound on stress and exhaustion. Adv Therapy 19, 141–150 (2002). https://doi.org/10.1007/BF02850270

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02850270

Keywords

Navigation