Abstract
Currently, thyroidectomies are performed with very little morbidity. This study was undertaken to investigate whether the use of the harmonic scalpel during thyroid surgery has any advantage over the conventional technique. Eighty patients were randomly assigned to 2 groups. The patients in group 1 (n=40) underwent thyroidectomy performed with conventional knot tying and the electrocautery technique; in patients in group 2 (n=40), the harmonic scalpel was used for the procedure. Significant differences were observed between these 2 surgical techniques in terms of operative time, number of ligatures used, amount of bleeding, average length of incision, total amount of drainage fluid, and cosmetic satisfaction (P<.05). With the harmonic scalpel technique, there was a nearly 18% reduction in operative time. No significant differences were noted between mean hospital stay and postoperative pain (P>.05). No patient in either group had permanent recurrent laryngeal nerve palsy or hypoparathyroidism. The harmonic scalpel significantly shortens the duration of thyroidectomies; it can be used safely and effectively in thyroid surgery with no additional morbidity.
Similar content being viewed by others
References
Cordon C, Fajardo R, Ramirez J, Herrera MF. A randomized, prospective, parallel group study comparing the harmonic scalpel to electrocautery in thyroidectomy.Surgery. 2005; 137: 337–341.
Hambley R, Hebda PA, Abell E, Cohen BA, Jegasothy BV. Wound healing of skin incisions produced by ultrasonically vibrating knife, scalpel, electrosurgery, and carbon dioxide laser.J Dermatol Surg Oncol. 1988; 14: 1213–1217.
Carroll T, Ladner K, Meyers AD. Alternative surgical dissection techniques.Otolaryngol Clin North Am. 2005; 38: 397–411.
Franklin EJ, Seetharam S, Lowney J, Horgan PG. Randomized, clinical trial of Ligasure vs conventional diathermy in hemorrhoidectomy.Dis Colon Rectum. 2003; 46: 1380–1383.
Voutilainen PE, Hauglund CH. Ultrasonically activated shears in thyroidectomies: a randomized trial.Ann Surg. 2000; 231: 322–328.
Siperstein AE, Berber E, Morkoyun E. The use of the harmonic scalpel vs conventional knot tying for vessel ligation in thyroid surgery.Arch Surg. 2002; 137: 137–142.
Shemen L. Thyroidectomy using the harmonic scalpel: analysis of 105 consecutive cases.Otolaryngol Head Neck Surg. 2002; 127: 234–238.
Amaral JF. Ultrasonic dissection.Endosc Surg Allied Technol. 1994; 2: 181–185.
Shen WT, Baumbusch MA, Kebelew E, Duh QY. Use of the electrothermal vessel sealing system versus standard vessel ligation in thyroidectomy.Asian J Surg. 2005; 28: 86–89.
Miccoli P, Berti P, Raffaelli M, Materazzi G, Conte M, Galleri D. Impact of harmonic scalpel on operative time during video-assisted thyroidectomy.Surg Endosc. 2002; 16: 663–666.
Miccoli P, Berti P, Raffaelli M, Materazzi G, Baldacci S, Rossi G. Comparison between minimally invasive video-assisted thyroidectomy and conventional thyroidectomy: a prospective randomized study.Surgery. 2001; 130: 1039–1043.
Ortega J, Sala C, Flor B, Lledo S. Efficacy and cost-effectiveness of the UltraCision harmonic scalpel in thyroid surgery: an analysis of 200 cases in a randomized trial.J Laparoendosc Adv Surg Tech A. 2004; 14: 9–12.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kilic, M., Keskek, M., Ertan, T. et al. A prospective randomized trial comparing the harmonic scalpel with conventional knot tying in thyroidectomy. Adv Therapy 24, 632–638 (2007). https://doi.org/10.1007/BF02848788
Issue Date:
DOI: https://doi.org/10.1007/BF02848788