Abstract
Gastroesophageal reflux (GER) is implicated in the pathogenesis of respiratory symptoms in childhood. It should be taken into account especially in the differential diagnosis of children presenting with wheezing.
Although, oesophageal pH monitorisation has been reported to be the best technique in the evaluation of GER, radionuclide studies have also been shown to be very sensitive recently. In this study, 82 children presenting with recurrent wheezing (n=74) and/or vomiting (n=28) (mean age 17.4 months; range 3–48 months) were evaluated. GER scintigraphy was performed to determine the frequency of GER. GER was determined in 18 of the 82 cases (21.9%). The GER was found in 21.1% of children with recurrent wheezing and in 16.6% of children suffering from recurrent vomiting.
GER scintigraphy should be kept in mind in the evaluation of children with the complaint of recurrent wheezing since it is a noninvasive and easily applicable method.
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References
Vandenplas Y. Oesophageal pH monitoring for gastro-oesophageal reflux in infants and children. J Wiley and Sons, England, 1992.
Balisteri WF, Farrell MK. Gastroesophageal reflux in infants.N Engl J Med 1983; 309: 790–3.
Vandenplas Y, Gayvaerts H, Helven Het al. Gastroesophageal reflux, as measured by 24 hours pH monitoring in 509 healthy infants screened for risk of sudden infant death syndrome.Pediatrics 1991; 88: 834–40.
Orenstein SR. Gastroesophageal relux. In: Wyllie R, Hyams JS (eds).Pediatric Gastrointestinal Disease. Philadelphia, WB. Saunders Co. 1993; 337–41.
Vandenplas Y. Reflux esophagitis in infant and children: A report from working group on gastro-eosophageal reflux disease of the European Society of Pediatric Gastro-enterology and Nutrition.J Pediatr Gastroenterol Nutr 1994; 1: 413–22.
Stephen TC, Younoszoi MK. Massey MPet al. Diagnosis of gastroesophageal reflux in pediatrics.JKY Med Assoc 1994; 92: 188–91.
Jolley SG, Johnson DG, Herbst JJ,et al. An assessment of gastroesophageal reflux in children by extended pH monitoring of the distal eosphagus.Surgery 1978; 84: 16–24.
Gonzales Fernandez F. Aruguelles Martin F, Rodriquez de Quesada Bet al. Gastroesophageal scintigraphy: A useful screening test for GER reflux.J Pediatr Gastroenterol Nutr 1987; 6: 217–9.
Tucci F, Resti M, Fontana Ret al. Gastroesophageal reflux and bronchial asthma.J Pediatr Gastroenterol Nutr 1993; 17: 265–70.
Orenstein SR, Orenstein DM. Gastroesophageal reflux and respiratory disease in children.J Pediatr 1988; 112: 847–58.
Crausaz FM, Fauez G. Aspiration of solid food particles into lungs of patients with gastroesophageal reflux and chronic bronchial disease.Chest 1988; 93: 376–8.
Mansfield LE, Stein MR. Gastroesophageal reflux and asthma: A possible reflex mechanism.Ann Allergy 1978; 41: 224–6.
Sontag SJ, Khandelwas S, Miller T,et al. Most asthmatics have gastroesophageal reflux with or without bronchodilator therapy.Gastroenterology 1990; 613: 20.
Vandenplas Y, Sacre-Smits L. Continuous 24-hour esophageal pH monitoring in 285 asymptomatic infants 0–15 months old.J Pediatr Gastroenterol Nutr 1987; 6: 220–4.
Grill BB. Twenty-four-hour esophageal pH monitoring: What's the score?J Pediatr Gastroenterol Nutr 1992; 4: 249–51.
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Karaman, Ö., Uzuner, N., Deĝirmenci, B. et al. Results of the gastroesophageal reflux assessment in wheezy children. Indian J Pediatr 66, 351–355 (1999). https://doi.org/10.1007/BF02845522
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DOI: https://doi.org/10.1007/BF02845522