Abstract
Perinatal risk factors were studied among 50 cases of neonatal septicemia and 200 matched normal neonates during one year period. The consanguinity among parents, birth order and sex of the baby did not increase the risk for developing septicemia. There was significant increase in the risk for septicemia when the duration of labour was more than 24 hours (P<0.01), time interval between rupture of membrane and delivery of baby was more than 12 hours (P < 0.001), liquor was meconium stained or foul smelling (P<0.001) and delivery was operative (P<0.01), The neonatal factors identified with risk for septicemia were preterm delivery (P<0.01), low birth weight (P<0.01), birth asphyxia (P < 0.001) assisted ventilation (P < 0.001) and intravenous alimentation (P<0.02). Identification of high risk pregnancies and appropriate management can minimize many of the above risk factors which in turn will reduce the occurrence of neonatal sepsis.
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Thora S, Awadhiya A, Chansoria A, Kaul KK. Perinatal and infant mortality in urban slums under ICDS scheme.Indian Pediatr 1986; 23: 595–598.
Kumari S, Pruthi PK, Mehra R, Gujral VV. Infection scoring in early neonatal infections.Indian J Pediatr 1983; 50: 177–181.
Takkar VP, Bhakoo ON, Narang A. Scoring system form prediction of early neonatal infection.Indian Pediatr 1974; 11: 597–600.
Bannet R, Eritsson M, Zettorstorm R. Increasing incidence of neonatal septicemia, causative organisms and predisposing risk factors.Acta Pediatr Scand 1981; 70: 207–210.
Harris MC, Polm RA. Neonatal septicemia.Ped Clin North Am 1983; 30: 243–258.
Gluck L, Wood HF, Fousek MD. Septicemia of the newborn.Pediatr Clin North Am 1966; 13: 1131–1147.
Guha DK, Jaspal D, Das KMS et al. Out-come of neonatal septicemia: A clinical and bacteriological profile.Indian Pediatr 1978; 15: 423–427.
bhakoo ON, Singh M. Perinatal risk factors in neonatal bacterial sepsis.Indian J Pediatr 1988; 55: 941–946.
Dunham EC. Septicemia in newborn.Am J Dis Child 1933; 45: 229–253.
Sinha N, Deb A, Mukherjee AK. Septicemia in neonates and early infancy.Indian J Pediatr 1986; 53: 249–256.
Prema A.Consanguinity and its effect on morbidity and mortality of newborns in Pondicherry. MD Thesis submitted to Madras University 1979.
Mehrotra N, Kumar A, Chansoria M, Kaul KK. Neonatal septicemia: Correlation of maternal and neonatal factors to positive bacterial cultures.Indian Pediatr 1985; 22: 275–280.
Choudhwry, Srivastava G, Aggrawal DSet al. Bacteriological study of neonatal infection.Indian Pediatr 1975; 12: 459–463.
Habel AH, Sandor GS, Conn NK, McCrae WM. Premature rupture of membranes and effect of prophylactic antibiotics.Arch Dis Child 1972; 47: 401–404.
Bada HS, Alojipan LC, Andrews BF. Premature rupture of membrane and its effect on the newborn.Pediatr Clin North Am 1977; 24: 491–499.
Anderson GS, Green CA, Neligan GAet al. Congenital bacterial pneumonia.Lancet 1962; 2: 585–587.
Wilson MG, Armstrong DH, Nelson RC, Boak RA. Prolonged rupture of fetal membrane.Am J Dis Child 1964; 107: 138–146.
Jeffery H, Mitchison R, Wigglesworth JS, Davies PA. Early neonatal bacteraemia—Comparison of group B streptococcal, other gram positive and gram negative infection.Arch Dis Child 1977; 52: 683–686.
Yoder MC, Polin RA. Immunotherapy of neonatal septicemia.Pediatr Clin North Am 1987; 33: 481–502.
Christensen RD, Macfarlane JL, Taylor NL et al. Blood and marrow neutrophils during experimental group B streptococcal infection. Quantification of the stem cells, proliferative, storage and circulating pools.Pediatr Res 1982; 16: 549–555.
Kuruvilla AC. Neonatal septicemia.Indian J Pediatr 1988; 55: 225–233.
Harris H, Wirschafter D, Cassady G. Endotracheal intubation and its relationship to bacterial colonoization and systemic infection in newborn.Pediatrics 1976; 58: 816–820.
Christo GG, Chandran S, Shivananda PGet al. Coagulase negative staphylococcus sepsis in infants.Indian Pediatr 1988; 25: 338–341.
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Raghavan, M., Mondal, G.P., Bhat, B.V. et al. Perinatal risk factors in neonatal infections. Indian J Pediatr 59, 335–340 (1992). https://doi.org/10.1007/BF02821801
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DOI: https://doi.org/10.1007/BF02821801