Abstract
Sixty four cases of acute encephalopathy syndrome admitted to the Vani Vilas Children's Hospital, Bangalore, during the period April 1973 through January 1974 were studied. The median age was 4.84 years. There was no difference in the sex ratio. Maximum number of cases were admitted during the winter months. Cases tended to cluster in certain congested localities of the city among the lower socio-economic strata. 53 (89.8%) of the 59 patients, who could be followed up to the end, expired. The clinical and biochemical findings in many patients were suggestive of Reye's syndrome. Though 6 strains of coxsackie viruses were isolated from 160 specimens processed for virus isolation, they could not be incriminated as etiological agents in majority of patients.
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Chari MV, Swamy TV: Jamshedpur fever. Br Med J 2: 1298, 1955
Teneja PN: Virus encephalitis in Delhi. Ind J Child Hlth 4: 186, 1955
Gupta NP, Paul S, Bal A, Gupta SP, Govil KK, Bhadry T, Bajpai PC, Dixit SK: Cytopathogenic agents from 1958 epidemic of encephalitis in Lucknow. Ind J Path Bact 2: 248, 1959
Indian Council of Medical Research: Acute encephalopathy syndrome in children. Tech Rep Ser. No. 3, 1970
John TJ, Mammen KC, Date A, Kamath KR: Acute encephalopathy with fatty degeneration of the viscera: a study of three cases in India. Indian J Med Res 57: 1865, 1969
Joseph A, John TJ: Reye's syndrome in siblings. Indian Pediatr 8: 174, 1971
Chandrasekaran R, Vijayakumar, Bannerjee C. Walia BNS, Bhagwat AG: Reye's syndrome: clinical course and follow up of survivors. Ind. Pediatr 10: 377, 1973
Kalra V, Sachdev HPS, Menon PSN: Reye's syndrome in Delhi. Indian J Pediat 48: 585, 1981
Merchant RH, Bajaj RT, Shah KN, Desai MP, Gharpure SV: Reye's syndrome in Bombay, Indian J Pediat 48: 581, 1981
Deshpande DH, Srinivas HV, Vasudev Rao T: Reye's syndrome: report of six autopsied cases. Ind Pediatr 17: 3, 1980
Feldman RA, Christopher S, George S, Kamath KR, John TJ: Infection and disease in a group of south Indian families, III. Virological methods and a report of the frequency of enteroviral infection in preschool children. Am J Epidemiol 92: 357, 1970
Reye RDK, Morgan G, Baral J: Encephalopathy and fatty degeneration of the viscera: A disease entity in childhood. Lancet 2: 749, 1963
Center for Disease control: Follow up on Reye syndrome—United states. Epidemiologic notes and reports. Morbidity and Mortality weekly report 29: 321, 1980
Komerwar AM, Muralidharan D, Krishnamurthy V, Ramachandran CR: A study of air pollution in Bangalore. Paper presented at the 31 st National conference of Indian Association of Occupational Health, Jamshedpur, 1981
Glick TH, Ditchek NT, Salitsky S, Freimuth EJ: Acute encephalopathy and hepatic dysfunction associated with chicken pox in siblings. Am J Dis Child 119: 68, 1970
Corey L, Rubin RJ, Hattwick MAW, Noble G, Cassidy E: A nation wide outbreak of Reye's syndrome: its epidemiologic relationship to influenza B. Am J Med 61: 615, 1976
Halsey NA, Hurwitz ES, Meiklejohn G, Todd WA, Edell T, Todd JK, Mclntosh K: An epidemic of Reye syndrome associated with influenza A (H1N1) in Colorado. J Pediatr 97: 535, 1980
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Benakappa, D.G., Prasad, S.R., Sastry, N.S.C. et al. Acute encephalopathy syndrome in Bangalore. Indian J Pediatr 50, 121–127 (1983). https://doi.org/10.1007/BF02821429
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DOI: https://doi.org/10.1007/BF02821429