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Anti-trichomonal IgA antibodies in trichomoniasis before and after treatment

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Abstract

Anti-trichomonal IgA antibodies were estimated by enzyme-linked immunosorbent assay (ELISA) in serum and vaginal secretions of 25 symptomatic and 25 asymptomaticTrichomonas vaginalis positive patients before and after treatment and in 25 age-matched controls. Significantly higher levels of antitrichomonad IgA antibodies were found inT. vaginalis positive patients when compared to control subjects, especially in vaginal secretions. In addition, a significant decrease in these antibodies was observed after treatment, which was more pronounced in vaginal secretions. It seems that anti-trichomonal IgA antibodies in serum and more so in vaginal secretions are directly related to and specific to the presence ofT. vaginalis in the urogenital tract.

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Authors and Affiliations

  1. Department of Parasitology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India

    P. Sharma, N. Malla & R. C. Mahajan

  2. Department of Obstetrics, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India

    I. Gupta

  3. Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India

    N. K. Ganguly

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  1. P. Sharma
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  2. N. Malla
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  3. I. Gupta
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  4. N. K. Ganguly
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  5. R. C. Mahajan
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Sharma, P., Malla, N., Gupta, I. et al. Anti-trichomonal IgA antibodies in trichomoniasis before and after treatment. Folia Microbiol 36, 302–304 (1991). https://doi.org/10.1007/BF02814365

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  • DOI: https://doi.org/10.1007/BF02814365

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