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Prevalence of hepatitis-G virus and hepatitis-C virus infection in patients with non-Hodgkin's lymphoma

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Abstract

Several studies have reported that hepatitis-C virus may have a role in the development of non-Hodgkin's lymphoma. Hepatitis-G virus has hepatitis-C virus like characteristics. The possible association between hepatitis-G virus infection and non-Hodgkin's lymphoma is not clear. The aim of this study was to determine the prevalence of hepatitis-G virus and hepatitis-C virus infection in patients with non-Hodgkin's lymphoma without blood transfusion. Forty-four patients with non-Hodgkin's lymphoma were enrolled in the study. Serum samples derived from the patients were tested for antibodies against hepatitis-C virus by ELISA. Hepatitis-G virus and hepatitis-C virus RNA were detected by reverse transcription-polymerase chain reaction. Only two of 44 patients (5%) with non-Hodgkin's lymphoma were positive for Anti-HCV and hepatitis C virus RNA. One patient had low grade non-Hodgkin's lymphoma with follicular mixed histopathology while the other had intermediate grade with diffuse large cell histopathology. Hepatitis-G virus infection was detected in none of the patients. We concluded that hepatitis-G virus does not seem to be in association with non-Hodgkin's lymphoma.

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Authors and Affiliations

  1. Department of Medical Oncology, Baskent University Faculty of Medicine, 06490, Ankara, Turkey

    A Arican

  2. Fatih Caddesi, Fatih Sitesi No: 174/18, 06300, Keçiören, Ankara, Turkey

    A Arican

  3. Ankara University Institute of Hepatology, Ankara, Turkey

    T Sengezer, M Bozdayi, H Bozkaya & Ö Uzunalimoĝlu

  4. Department of Internal Medicine, Ankara University Faculty of Medicine, 06100, Ankara, Turkey

    E Üçgül

  5. Department of Medical Oncology, Ankara University Faculty of Medicine, 06100, Ankara, Turkey

    D Dinçol

Authors
  1. A Arican
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  2. T Sengezer
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  3. M Bozdayi
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  4. H Bozkaya
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  5. E Üçgül
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  6. D Dinçol
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  7. Ö Uzunalimoĝlu
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Arican, A., Sengezer, T., Bozdayi, M. et al. Prevalence of hepatitis-G virus and hepatitis-C virus infection in patients with non-Hodgkin's lymphoma. Med Oncol 17, 123–126 (2000). https://doi.org/10.1007/BF02796207

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  • DOI: https://doi.org/10.1007/BF02796207

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