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Rubidium—A possible essential trace element

1. The rubidium content of whole blood of healthy and dietetically treated children

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Abstract

The rubidium content of whole blood was estimated by instrumental neutron activation analysis. In 46 healthy children it amounts to {ie193-1} g/g dry weight. There was no difference between the values found for infants, toddlers, and school children. In 29 dietetically treated patients with phenylketonuria and maple-syrup-urine disease the values were significantly lower than in healthy children. During the first three months of diet therapy the rubidium levels remained in the lower range of the normal values, decreasing to about 60% of the mean of normal values later on. With increasing length of diet therapy these values tended to decrease. It remains questionable whether these decreased levels reflect only an induced biochemical phenomenon without biological importance, or whether they are the first signs of a deficiency syndrome.

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Authors and Affiliations

  1. University Children’s Hospital C, University of Düsseldorf, Moorenstrasse 5, D-4000, Düsseldorf 1, Federal Republic of Germany

    Ingrid Lombeck & H. J. Bremer

  2. Medical Institute, Nuclear Research Centre of Jülich GmbH, D-5170, Jülich, Federal Republic of Germany

    K. Kasperek & L. E. Feinendegen

Authors
  1. Ingrid Lombeck
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  2. K. Kasperek
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  3. L. E. Feinendegen
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  4. H. J. Bremer
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Lombeck, I., Kasperek, K., Feinendegen, L.E. et al. Rubidium—A possible essential trace element. Biol Trace Elem Res 2, 193–198 (1980). https://doi.org/10.1007/BF02785354

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  • DOI: https://doi.org/10.1007/BF02785354

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