Abstract
Plasma molybdenum concentrations were determined in children, ages two to 12 yr, with and without phenylketonuria (PKU). Mean plasma molybdenum concentrations did not differ significantly between the children with PKU (1.33±0.5 μg/L) and without PKU (1.75±0.8 μg/L). Plasma molybdenum concentrations in both groups of children ranged from <1 to 3 μg/L.
When data from all children were combined and then separated based on gender, mean plasma molybdenum levels did not differ significantly between 9 females (1.56±0.68 μg/L) and 12 males (1.58±0.76 μg/L). Data were also combined and mean (±SD) plasma molybdenum concentrations calculated for age groups. Two children aged 1 to <4 yr had plasma molybdenum concentrations of 1.0 μg/L, and six children aged 4 to <7 yr had mean (±SD) plasma molybdenum concentrations of 1.5±0.8 μg/L. Eleven children aged 7 to <11 yr had a mean plasma molybdenum concentration of 1.7±0.7 μg/L, and two children 11 to <14 yr had plasma molybdenum concentrations of 1 μg/L and 2 μg/L. Plasma molybdenum concentrations did not differ significantly among children in the age groups.
Similar content being viewed by others
References
T. A. Tsongas, R. R. Meglen, P. A. Walravens, and W. R. Chappell,Am. J. Clin. Nutr. 33, 1103 (1980).
J. A. Pennington and J. W. Jones,J. Am. Diet. Assoc. 87, 1644 (1987).
Food and Nutrition Board, Commission on Life Sciences, National Research Council,Recommended Dietary Allowances, 10th ed., National Academy Press, Washington, D.C., 1989, pp. 243–246.
Perkin Elmer,Techniques in Graphite Furnace Atomic Absorption Spectrophotometry, Perkin Elmer, Norwalk, CT, 1985 p. 128.
J. Versieck,Clin. Lab. Sci. 22, 97 (1984).
J. Versieck, J. Hoste, F. Barbier, L. Vanballenberghe, J. D. Rudder, and R. Cornelis,Clin. Chim. Acta 87, 135 (1978).
D. Bougle, J. Voirin, F. Bureau, J. F. Duhamel, G. Muller, and M. Drosdowsky,Acta Paediatr. Scand. 78, 319 (1989).
W. H. Allaway, J. Kubota, F. Losee, and M. Roth,Arch. Environ. Health 16, 342 (1968).
J. Versieck and R. Cornelis,Anal. Chim. Acta 116, 217 (1980).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gropper, S.S., Yannicelli, S. Plasma molybdenum concentrations in children with and without phenylketonuria. Biol Trace Elem Res 38, 227–231 (1993). https://doi.org/10.1007/BF02785307
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02785307