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HTLV-I, infective dermatitis, and tropical spastic paraparesis

  • Neurodegenerative Diseases
  • Part II: Transmissible Neurodegenerative Disorders (Proceedings of the symposium “Transmissible and Nontransmissible Neurodegenerative Disorders” held in Ocho Rios, Jamaica, February 28–March 5, 1993)
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Molecular Neurobiology Aims and scope Submit manuscript

Abstract

Since human T-cell lymphotropic virus (HTLV-I) was identified in 1980 as causing human disease, it has been etiologically associated with adult T-cell lymphoma/leukemia (ATL) and tropical spastic paraparesis (TSP). More recently, several new diseases have been reported in association with this virus, including infective dermatitis of Jamaican children, which we reported in 1990.

Studies on infective dermatitis have shown that these children have abnormalities of immune function, and some develop other HTLV-I associated disorders, including TSP. This paper reviews the work done on infective dermatitis to date, and explores the association with TSP.

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Authors and Affiliations

  1. Department of Medicine-Dermatology Unit, University of the West Indies, Mona, Jamaica

    L. La Grenade

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  1. L. La Grenade
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La Grenade, L. HTLV-I, infective dermatitis, and tropical spastic paraparesis. Mol Neurobiol 8, 147–148 (1994). https://doi.org/10.1007/BF02780665

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  • DOI: https://doi.org/10.1007/BF02780665

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