Summary
The importance of performing an endometrial biopsy in women preparing for oocyte donation goes beyond confirming the histologic response to hormone replacement therapy. Additional information related to uterine architecture, ease of embryo transfer, status of the ovaries, and patient compliance is also gained. Finally, the return visit provides an opportunity to discuss plans for the upcoming cycle. Whereas this report does not specifically address the question as to how many pregnancies were contingent upon the satisfactory performance of the mock cycle, we estimate that due to a combination of factors (i.e., lack of endometrial response, patient noncompliance, difficult embryo transfer), the likelihood of pregnancy in many cases would have been substantially reduced had the preliminary cycle not been attempted.
References
Morris RS, Sauer MV: Oocyte donation in the 1990’s and beyond. Assist Reprod Rev 1993;3:211–217
Sauer MV, Paulson RJ, Macaso TM, Hernandez MM, Lobo RA: Establishment of a nonanonymous donor oocyte program: Preliminary experience at the University of Southern California. Fertil Steril 1989;52:433–436
Noyes RW, Hertig AT, Rock J: Dating the endometrial biopsy. Fertil Steril 1950;1:3–25
Grunfeld L, Walker B, Bergh PA, Sandler B, Hofman G, Navot D: High resolution endovaginal ultrasonography of the endometrium: A noninvasive test for endometrial adequacy. Obstet Gynecol 1991;78:200–204
Li TC, Warren MA, Cooke ID: Is the measurement of oestradiol/progesterone ratios in the peri-implantation period of any value in predicting endometrial development? Hum Reprod 1993;8:374–378
Navot D, Bergh PA, Williams M, Garrisi CJ, Guzman I, Sandler B, Fox J, Schreiner-Engel P, Hofman GE, Grunfeld L: An insight into early reproductive processes through the in-vivo model of ovum donation. J Clin Endocrinol Metab 1991;72:408–414
Devroey P, Palermo G, Bourgain C, Van Waesberghe L, Smitz J, Van Steirteghem AC: Progesterone administration in patients with absent ovaries. Int J Fertil 1989;34:188–193
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sauer, M.V., Paulson, R.J. & Moyer, D.L. Assessing the importance of endometrial biopsy prior to oocyte donation. J Assist Reprod Genet 14, 125–127 (1997). https://doi.org/10.1007/BF02765782
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02765782