Abstract
In this study we investigated the distribution of collagen types I–V in the human iris at the fine-structural level using cryoultramicrotomy and London Resin White plastic embedding. Collagen type I was shown to be present in the basement membrane of iris vessels, in contrast to type III, which was absent; both types I and III were present in the iris stroma. Collagen type IV was a major component of basement membranes of vascular cells, myoepithelial cells, fibroblasts and epithelial cells. Types II and V were absent. Both cryo and plastic embedding techniques produced closely comparable results.
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Supported by the WH Ross Foundation for the Prevention of Blindness
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Konstas, A.G., Marshall, G.E. & Lee, W.R. Immunocytochemical localisation of collagens (I–V) in the human iris. Graefe’s Arch Clin Exp Ophthalmol 228, 180–186 (1990). https://doi.org/10.1007/BF02764315
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DOI: https://doi.org/10.1007/BF02764315