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Immune reconstitution syndrome in a child with TB and HIV

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Abstract

Immune reconstitution syndrome (IRS) is the transient worsening or appearance of new signs, symptoms, or radiological manifestation of an opportunistic infection occurring after the initiation of Highly active antiretroviral therapy (HAART) and is not due to treatment failure or new infection. We describe a case of a HIV infected child with tubercular (mediastinal) lymphadenitis with worsening of clinical and radiological features on starting HAART.

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Authors and Affiliations

  1. Tuberculosis Research Centre, Mayor V.R. Ramanathan Road, 600 031, Chetput, Chennai, India

    G. Narendran & Soumya Swaminathan (Sr. Grade Deputy Director, HIV/AIDS Division, Tuberculosis Research Centre)

  2. Tambaram Sanatorium, Govt. Hospital of Thoracic Medicine, Mayor V.R Ramanathan Road, 600 031, Cheptur, Chennai, India

    S. Sathish & S. Rajasekaran

Authors
  1. G. Narendran
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  2. Soumya Swaminathan
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  3. S. Sathish
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  4. S. Rajasekaran
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Corresponding author

Correspondence to Soumya Swaminathan.

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Narendran, G., Swaminathan, S., Sathish, S. et al. Immune reconstitution syndrome in a child with TB and HIV. Indian J Pediatr 73, 627–629 (2006). https://doi.org/10.1007/BF02759931

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  • DOI: https://doi.org/10.1007/BF02759931

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