Abstract
The case of a neonate is presented who had early onset seizure associated with hypocalcemia, hyperphosphatemia, and raised parathyroid hormone. The infant did not have any stigmata of pseudohypoparathyroidism. The hypocalcemia was initially resistant to calcium therapy, but responded to vitamin D analog therapy. The diagnosis of ‘neonatal pseudohypoparathyroidism’ was entertained; the infant remained stable and seizure-free with normal serum biochemistry during 3 months of follow-up.
This is a preview of subscription content, log in via an institution to check access.
References
DiGeorge AM. Pseudohypothyroidism. In Behrman Er, Kliegmann RM, Arvin AM, eds.Nelson Textbook of Pediatrics. 16th edn. Philadelphia; WB Saunders Co, 2000; 1718–1719.
Vasicek TJ, Mc Devitt Be, Freeman MW, Fennick BJ, Hendy GH, Potts Jet al. Nucleotide sequence of human PTH gene.Proc Natl Acad Sci USA 1983; 80: 2127–2131.
Drezner MK, Neelson FA. Pseudohypoparathyroidism.In Stanbury JB, Wyngaarden JB, Friderickson DS, eds. The metabolic basis of inherited disease. New York; Mc Graw-Hill, 1983; 1508–1527.
Manzar S. Transient pseudohypoparathyroidism and neonatal seizure.J Trop Pediatr 2001; 47: 113–114.
Minagawa M, Yasuda T, Kobayashi Y, Niimi H. Transient pseudohypoparathyroidism in neonate.Eur J Endocrinol 1995; 133: 151–155.
Sajitha S, Krishnamoorthy PN, Shenoy UV. Pseudohypoparathyroidism in Newborn—A Rare Presentation.Indian Pediatrics 2003; 40: 47–49.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Narang, M., Salota, R. & Sachdev, S.S. Neonatal pseudohypoparathyroidism. Indian J Pediatr 73, 97–98 (2006). https://doi.org/10.1007/BF02758270
Issue Date:
DOI: https://doi.org/10.1007/BF02758270