Skip to main content
Log in

Juvenile rheumatoid arthritis in India—rarity of antinuclear antibody and uveitis

  • Symposium: Rheumatology Part I
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Juvenile chronic arthritis is a heterogenous disease, having different subtypes. Among our 89 patients with juvenile chronic arthritis, we did not find even one patient with early onset pauciarticular disease with uveitis and antinuclear antibody positivity. Further, the prevalence of anti-nuclear antibodies and anti-histone antibodies was very low whereas the prevalence of rheumatoid factor was similar to that reported from Western countries. Thus, the spectrum of juvenile chronic arthritis in India differs from that seen in the west. Larger population based studies of the disease are thus needed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Benjamin CM. Review of UK data on the rheumatic diseases-1. Juvenile chronic arthritis.Br J Rheumatol 1990; 29: 231–233.

    Article  PubMed  CAS  Google Scholar 

  2. Aggarwal A, Misra R. Juvenile chronic arthritis in India: Is it different from that seen in the Western countries?Rheumatol International 1994; 14: 53–56.

    Article  CAS  Google Scholar 

  3. Preiur AM, Ansell, BM, Bardfield Ret al. Is onset type evaluated during the first 3 months of disease satisfactory for defining the subgroup of juvenile chronic arthritis? A EULAR cooperative study (1983–1986).Clin Exp Rheumatol 1990; 8: 321–325.

    Google Scholar 

  4. Mcgill NW, Gow PJ. Juvenile rheumatoid arthritis in Auckland: a longterm followup with particular reference to uveitis.Aust N Z J Med 1987; 17: 305–308.

    PubMed  CAS  Google Scholar 

  5. Mcdougall P, Hill DJ. Juvenile chronic arthritis.Med J Aust 1981; 2: 89–92.

    Google Scholar 

  6. Parkodi R, Ramakrishnan S, Krishnamurthy Vet al. Pattern of rheumatic diseases in south India. IV. Clinical profile of juvenile rheumatoid arthritis.J Assoc Physicians India 1990; 38: 771–773.

    Google Scholar 

  7. Malaviya AN, Narayanan K. Juvenile chronic arthritis in India.Indian J Pediatr 1981; 48: 659–667.

    PubMed  CAS  Google Scholar 

  8. Gupta D, Aggarwal A, Misra R. Auto-antibodies in juvenile chronic arthritis (JCA) of North Indian children: Is it different from the west?Proceedings of the Annual Conference of Indian Rheumatism Association. New Delhi. 1993.

  9. Lawrence JM III, Moore TL, Osborn TGet al. Auto-antibodies in juvenile rheumatoid arthritis.Semin Arthritis Rheum 1993; 22: 265–274.

    Article  PubMed  Google Scholar 

  10. Aggarwal A, Dabadghao S, Naik S, Misra R. Serum IgM rheumatoid factor by enzyme linked immunosorbent assay (ELISA) delineates a subset of patients with deforming joint disease in seronegative juvenile chronic arthritis.Rheumatol International 1994; 14: 135–138.

    Article  CAS  Google Scholar 

  11. Leak AM, Woo Patricia. Juvenile chronic arthritis, chronic iridocyclitis, and reactivity to histones.Ann Rheum Dis 1991; 50: 653–657.

    Article  PubMed  CAS  Google Scholar 

  12. Petty RE, Hunt DWC, Rollins DFet al. Immunity to soluble retinal antigens in patients with uveitis accompanying juvenile rheumatoid arthritis.Arthritis Rheum 1987; 30: 287–293.

    Article  PubMed  CAS  Google Scholar 

  13. Gupta D, Singh VK, Rajasingh Jet al. Cellular immune response of patients with juvenile rheumatoid arthritis to retinal antigens and their synthetic peptides.Immunol Res 1996 (in press).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aggarwal, A., Misra, R.N. Juvenile rheumatoid arthritis in India—rarity of antinuclear antibody and uveitis. Indian J Pediatr 63, 301–304 (1996). https://doi.org/10.1007/BF02751522

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02751522

Key words

Navigation