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Kinin receptors

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Summary

Rapid developments are expected in the molecular pharmacology of both B1, and B2 types of kinin receptors, since the underlying genetic structures are now known and widely studied. The consequences of kinin receptor duality and physiopathological regulation have not yet been fully appreciated. Medicinal chemistry is also an active front of research in kinin pharmacology, as more effective drugs targeted at kinin receptors are regularly reported. Various complementary molecular approaches (the receptor binding, cloning, immunoreacting, mutagenesis, inactivation, the study of regulation, allelic polymorphisms, and so forth) are expanding our knowledge of the role of kinins in allergy, inflammation, and singularly, renal medicine.

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  1. Centre de Recherche du Pavillon l’Hôtel-Dieu de Québec, Centre Hospitalier Universitaire de Québec, G1R 2J6, Québec, Canada

    Francois Marceau & Dimcho R. Bachvarov

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  1. Francois Marceau
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Marceau, F., Bachvarov, D.R. Kinin receptors. Clinic Rev Allerg Immunol 16, 385–401 (1998). https://doi.org/10.1007/BF02737658

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