Skip to main content
Log in

Systemic lupus erythematosus and sickle cell disease

  • Clinical Brief
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

A case of 10-year-old girl with an unusual association of sickle cell disease (SCO) with systemic lupus erythematosus (SLE) is presented. The report discusses the clues to the diagnosis of this rare combination with review of relevant literature and highlights the diagnostic dilemma that may arise because of the similarity of symptoms.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Emery H. Clinical aspects of systemic lupus erythema tosus in childhood.Pediatr Clin North Am 1986; 33:1177–92.

    PubMed  CAS  Google Scholar 

  2. Wilson WA, Nicholson GD, Hughes GRV,et al. Systemic lupus erythematosus and sickle cell anemia.BMJ 1976; 1:813.

    Article  PubMed  CAS  Google Scholar 

  3. Karthikeyan G, Wallace SL, Blum L. SLE and sickle cell disease.Arthritis Rheum 1978; 21:862–863.

    Article  PubMed  CAS  Google Scholar 

  4. White LF, Reeves JD. Polyarthritis and positive LE preparation in sickle hemoglobinopathies: a report of two cases.J Pediatr 1979; 95:1003–1004.

    Article  PubMed  CAS  Google Scholar 

  5. Shaw SE, Osher RH, Smith JL. Amaurosis fugax associated with SC hemoglobinopathy and lupus erythematosus.Am J Ophthalmol 1979; 87:281–285.

    PubMed  Google Scholar 

  6. Luban NCL, Boechx R, Barr O. Sickle cell anemia and SLE.J Pediatr 1980; 96: 1120.

    PubMed  CAS  Google Scholar 

  7. Warrier RP Sahney S, Walker H. Hemoglobin sickle cell disease and systemic lupus erythematosus.J Natl Med Assoc 1984; 76:1030–1031.

    PubMed  CAS  Google Scholar 

  8. Katasanis E, Hsu E, Luke KH,et al. Systemic lupus erythematosus and sickle cell hemoglobinopathies: a report of two cases and review of the literature.Am J Hematol 1987; 22 : 211–214.

    Article  Google Scholar 

  9. Eissa MM, Lawrence JM, III, McKenzie L, Little FM, Mankad VN, Yang YM. Systemic lupus erythematosus in a child with sickle cell disease.South Med J 1995; 88:1176–1178.

    PubMed  CAS  Google Scholar 

  10. Tan EM, Cohen AS, Fries JF,et al. The 1982 revised criteria for the classification of systemic lupus erythematosus (SLE).Arthritis Rheum 1982; 25:1271–1272.

    Article  PubMed  CAS  Google Scholar 

  11. Agenello V. Complement deficiency and SLE.Systemic Lupus Erythematosus. Lahita RG (ed). 1st Ed, New York, Wiley Med Publications, 1987; 565.

    Google Scholar 

  12. Johnson RB, Newman SL, Struth AG. An abnormality of the alternative pathway of complement activation in sickle cell anemia.N Eng J Med 1973; 288: 803–808.

    Article  Google Scholar 

  13. Carey JM, Polhill RB, Edmons SR,et al. Activity of the alternative complement pathway after splenectomy: comparison to activity in sickle cell disease and hypogammaglobulinemia.J Pediatr 1979; 95:964–969.

    Article  Google Scholar 

  14. Wilson WA, Hughes GRV, Lochmann PJ. Deficiency of factor B of the complement system in sickle cell disease.Clin Exp Immunol 1976; 23:56–60.

    Google Scholar 

  15. Wilson WA, Deceulaer K, Morgan AG. Sickle cell anemia, complement SLE.Arthritis Rheum 1979; 22:803.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shetty, A.K., Baliga, M.R., Gedalia, A. et al. Systemic lupus erythematosus and sickle cell disease. Indian J Pediatr 65, 618–621 (1998). https://doi.org/10.1007/BF02730909

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02730909

Key words

Navigation