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Clinico-bacteriological study of neonatal septicemia in Hubli

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Abstract

Septicemia is a leading cause of neonatal morbidity and mortality in India. In a study of 242 infants with septicemia conducted between March 1996 & June 1997 at Hubli, Karnataka, 43.39% infants had ‘very early onset’ sepsis (VOS), 40.08%, had ‘early onset’ sepsis (EOS), and 16.53% ‘late onset’ sepsis (LOS). 54.55% neonates had birth weight below 2000g and 39.67% were born before 37 weeks of gestation. The cardiorespiratory signs and jaundice were the most frequent clinical features. The blood culture positivity rate was 64.87%.Klebsiella species was the commonest causative pathogen found and multidrug resistance was frequent. The overall mortality rate was 47.52% and the case fatality rate in LOS was higher than in VOS and EOS (p < 0.001). The mortality was significantly higher in neonates with lower birth weight and lower gestational age (p < 0.001). The study underlines the importance of monitoring the various features of neonatal septicemia, as well as the drug resistance of the pathogens from the nurseries.

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Authors and Affiliations

  1. Department of Microbiology, Karnatak Institute of Medical Sciences, Hubli, 580 022, Karnataka

    Shashikala S. Tallur (Professor and Head)

  2. Department of Pediatrics, Karnatak Institute of Medical Sciences, Hubli, Karnataka

    A. V. Kasturi

  3. Department of Microbiology, Karnatak Institute of Medical Sciences, Hubli, Karnataka

    Shobha D. Nadgir

  4. Department of Microbiology, St. John’s Medical College, Bangalore

    B. V. S. Krishna

Authors
  1. Shashikala S. Tallur
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  2. A. V. Kasturi
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  3. Shobha D. Nadgir
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  4. B. V. S. Krishna
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Tallur, S.S., Kasturi, A.V., Nadgir, S.D. et al. Clinico-bacteriological study of neonatal septicemia in Hubli. Indian J Pediatr 67, 169–174 (2000). https://doi.org/10.1007/BF02723654

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